FISH - del13q or LSI D13S319 Test
Short Name: FISH del13q/LSI D13S319
Also known as: LSI D13S319 Test, del13q FISH Test, FISH for 13q deletion
FISH - del13q or LSI D13S319 Test test available at DNA Labs India for ₹6,000. Uses FISH on Whole Blood or Bone Marrow samples. Results in Sample collection by 4 pm daily; reports available in 4 days.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect deletions or translocations in the 13q14 region of chromosome 13, which are associated with hematological malignancies, aiding in diagnosis, prognosis, and treatment monitoring.
- Test Code
- 578
- Price
- ₹6,000
- Sample Type
- Whole Blood or Bone Marrow
- Result Time
- Sample collection by 4 pm daily; reports available in 4 days.
- Fasting Required
- No
- Method
- FISH
Sample Collection
Ensure the Chromosome & FISH analysis Requisition Form (Form 17) is duly filled and signed by the referring physician.
Method: Venipuncture for blood, bone marrow aspiration for marrow
Laboratory Analysis
Sample collection is performed by a trained phlebotomist or hematologist. For blood, a venipuncture is done; for bone marrow, an aspiration procedure under local anesthesia.
Report Delivery
The sample must be shipped at 18-22°C in sodium heparin tubes. Do not freeze the sample.
Timeline: Sample collection by 4 pm daily; reports available in 4 days.
Patient Instructions
About This Test
Who Should Get This Test
To detect deletions or translocations in the 13q14 region of chromosome 13, which are associated with hematological malignancies, aiding in diagnosis, prognosis, and treatment monitoring.
How to Prepare
- Complete Form 17 with patient details and clinical information
- Collect 5 mL whole blood or 4 mL bone marrow in 2 green top (sodium heparin) tubes
- Label tubes correctly with patient ID and date
- Ship at room temperature (18-22°C) without freezing
- Ensure delivery to lab within 48 hours of collection
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This FISH test is essential for identifying specific genetic deletions that guide treatment decisions in hematological malignancies, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample collected in incorrect container (not sodium heparin)
- Inadequate sample volume
- Frozen or hemolyzed sample
- Missing or incomplete requisition form
Understanding Your Results
Positive
Deletion detected in 13q14 region; associated with CLL or multiple myeloma, may influence treatment decisions
Negative
No deletion detected; further clinical evaluation may be needed if symptoms persist
Consult your doctor if you experience symptoms like unexplained weight loss, fatigue, easy bruising, or if you have been diagnosed with a hematological malignancy for treatment planning.
Limitations
- ⚠May not detect all submicroscopic abnormalities
- ⚠Requires specialized laboratory and skilled personnel
- ⚠False negatives possible in cases of low-level mosaicism
- ⚠Interpretation depends on clinical context
Risks & Considerations
- ●For blood draw: minor bruising, discomfort, or infection at puncture site
- ●For bone marrow aspiration: pain, bleeding, infection, or rare complications like nerve damage
Interfering Factors
- ●Poor sample quality or insufficient volume
- ●Contamination during sample handling
- ●Technical errors in FISH procedure
- ●Use of incorrect anticoagulant
Compare With Similar Tests
| Test | FISH - del13q or LSI D13S319 Test | Conventional Karyotype | FISH - del(17p) | Bone Marrow Biopsy |
|---|---|---|---|---|
| Comparison | FISH - del13q or LSI D13S319 Test |
Frequently Asked Questions
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