Immunophenotyping by Flow Cytometry CD117 Test
Short Name: CD117 Flow Cytometry Test
Also known as: c-kit Test, Flow Cytometry CD117
Immunophenotyping by Flow Cytometry CD117 Test test available at DNA Labs India for ₹3,500. Uses Flow Cytometry on Whole Blood or Bone Marrow samples. Results in Report available same day if sample collected by 9 am.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the CD117 test is to detect the presence and quantify the expression of CD117 surface protein on cells, aiding in the diagnosis and classification of blood cancers and disorders. It helps differentiate between various types of leukemia and lymphoma, guide treatment plans, and monitor disease progression or remission.
- Test Code
- 1053
- Price
- ₹3,500
- Sample Type
- Whole Blood or Bone Marrow
- Result Time
- Report available same day if sample collected by 9 am.
- Fasting Required
- No
- Method
- Flow Cytometry
Sample Collection
Provide a brief clinical history, including symptoms, family history, and current medications. No specific fasting is required.
Method: Venipuncture or Bone Marrow Aspiration
Laboratory Analysis
A healthcare professional will collect blood via venipuncture or bone marrow via aspiration under sterile conditions.
Report Delivery
The sample is labeled, stored appropriately, and shipped immediately at 18-22°C without refrigeration or freezing.
Timeline: Report available same day if sample collected by 9 am.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the CD117 test is to detect the presence and quantify the expression of CD117 surface protein on cells, aiding in the diagnosis and classification of blood cancers and disorders. It helps differentiate between various types of leukemia and lymphoma, guide treatment plans, and monitor disease progression or remission.
How to Prepare
- Collect 3 mL whole blood in EDTA and Sodium Heparin tubes or 2 mL bone marrow in Sodium Heparin tube
- Ship immediately at 18-22°C; do not refrigerate or freeze
- Specify time, date, and clinical details on the test request form
- Ensure proper labeling to avoid sample mix-ups
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"CD117 testing is vital for diagnosing hematologic malignancies and should be integrated with clinical findings and other tests for accurate patient management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample collected in incorrect container
- Hemolyzed, clotted, or insufficient volume
- Missing clinical details or request form
- Sample stored at wrong temperature or delayed beyond stability period
Understanding Your Results
Positive CD117 expression
Indicates presence of c-kit positive cells, common in certain leukemias like AML or mastocytosis; requires further correlation
Negative CD117 expression
Suggests absence or minimal c-kit positive cells; may not rule out all blood disorders
Elevated CD117+ cells
Could signal disease progression or relapse; monitor with additional tests
Normal cell distribution
Considers with reference ranges for age and gender; clinical context is essential
Consult a healthcare provider if you experience persistent symptoms like fatigue, infections, or bleeding, or if test results are abnormal or inconsistent with clinical findings.
Limitations
- ⚠This test is not standalone for diagnosis; must be correlated with clinical history and other tests
- ⚠May not detect all subtypes of hematologic malignancies
- ⚠Results can vary based on laboratory protocols and equipment calibration
Risks & Considerations
- ●Minor pain or bruising at the blood draw site
- ●Rare risk of infection at the puncture point
- ●Potential for discomfort during bone marrow aspiration
Interfering Factors
- ●Improper sample storage (temperature deviations)
- ●Hemolyzed or clotted samples
- ●Recent blood transfusions or medications affecting cell markers
- ●Delay in sample processing beyond 24 hours at room temperature
Compare With Similar Tests
| Test | Immunophenotyping by Flow Cytometry CD117 Test | Complete Blood Count (CBC) | Bone Marrow Biopsy | Other Flow Cytometry Panels |
|---|---|---|---|---|
| Comparison | Immunophenotyping by Flow Cytometry CD117 Test | CBC provides overall blood cell counts but lacks specific protein analysis like CD117 | Biopsy offers histological details, while flow cytometry CD117 provides molecular-level cell classification | CD117 is part of broader panels; specific markers vary based on suspected condition |
Frequently Asked Questions
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