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FKTN Gene Limb-girdle muscular dystrophy, autosomal recessive type 2M NGS Genetic Test

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FKTN Gene Limb-girdle muscular dystrophy, autosomal recessive type 2M NGS Genetic Test

Short Name: FKTN LGMD2M NGS Test

Also known as: LGMD2M Genetic Test, FKTN Gene NGS Analysis, Limb-Girdle Muscular Dystrophy Type 2M Confirmation Test

FKTN Gene Limb-girdle muscular dystrophy, autosomal recessive type 2M NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.

NGS Genetic TestChildren and Adults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

The purpose of this NGS genetic test is to identify disease-causing mutations in the FKTN gene associated with limb-girdle muscular dystrophy type 2M (LGMD2M). It aids in establishing a definitive diagnosis, differentiating from other muscular dystrophies, assisting in genetic counseling, and enabling informed reproductive decisions.

Test Code
4209
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks after the sample reaches the laboratory.
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No fasting is required. A genetic counseling session is recommended before the test to draw a pedigree chart and discuss the implications of the results.

Method: Venipuncture or FTA card spot

Step 2

Laboratory Analysis

A blood sample is collected by a trained phlebotomist. If using FTA card, a drop of blood is applied to the card and allowed to dry.

Step 3

Report Delivery

No special precautions are needed. You can resume your normal activities immediately.

Timeline: 3 to 4 weeks after the sample reaches the laboratory.

Patient Instructions

1
Before the Test:Genetic counseling and pedigree analysis will be performed before ordering this test.
2
During the Test:The blood/DNA sample is collected and sent to the lab. NGS analysis of the FKTN gene is performed.
3
After the Test:Results are shared in a clinical report, along with raw data files. A follow-up genetic counseling session is recommended.

About This Test

Who Should Get This Test

The purpose of this NGS genetic test is to identify disease-causing mutations in the FKTN gene associated with limb-girdle muscular dystrophy type 2M (LGMD2M). It aids in establishing a definitive diagnosis, differentiating from other muscular dystrophies, assisting in genetic counseling, and enabling informed reproductive decisions.

How to Prepare

  • Maintain the sample at room temperature if dispatch is within 24 hours.
  • If using FTA card, let the blood spot air dry thoroughly.
  • Label the sample with your name, date, and indicating test code if available.
  • Complete the request form and bring any prior genetic test reports if available.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Genetic testing for LGMD2M is essential for accurate diagnosis and family planning. NGS technology allows comprehensive analysis of the FKTN gene, providing timely and reliable results for clinical decision-making."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA tube (blood) or FTA card
Collection MethodVenipuncture or FTA card spot

Sample Stability

Blood: 24 hours at room temperature, 5-7 days at 2-8°C
Extracted DNA: stable for months at -20°C
FTA card blood spots: stable at room temperature for weeks
Sample Rejection Criteria:
  • Clotted or hemolyzed blood sample
  • Insufficient sample volume
  • Mislabeled sample or missing patient details
  • FTA card with insufficient blood spot or contamination

Understanding Your Results

This NGS test identifies changes in the FKTN gene. The presence of a pathogenic mutation in one or both alleles supports the diagnosis of LGMD2M, while the absence of detectable mutations does not completely rule out the disease.
Pathogenic variant detected: Diagnostic confirmation of LGMD2M in the appropriate clinical context.
Likely pathogenic variant detected: Likely diagnosis, additional family studies may be recommended.
Variant of uncertain significance (VUS): Further functional studies or segregation analysis may be needed.
No pathogenic variant detected: LGMD2M is less likely; other genetic causes should be considered.
⚠️ When to Consult a Doctor:

If you or a family member experience muscle weakness, gait alterations, frequent falls, or have a known family history of LGMD, consult a neurologist or clinical geneticist for evaluation and testing.

Risks & Considerations

  • ●Minimal risks associated with blood draw: slight pain, bruising, or lightheadedness.

Interfering Factors

  • ●Maternal cell contamination may affect results
  • ●Insufficient DNA quantity or quality
  • ●Low sequencing coverage in certain gene regions

Compare With Similar Tests

TestFKTN Gene Limb-girdle muscular dystrophy, autosomal recessive type 2M NGS Genetic Test
ComparisonFKTN Gene Limb-girdle muscular dystrophy, autosomal recessive type 2M NGS Genetic Test

Frequently Asked Questions

What is the cost of the FKTN gene NGS genetic test for LGMD2M?
The test costs INR 20,000 at DNA Labs India.
What sample is required for this test?
Blood, extracted DNA, or one drop of blood on an FTA card.
Do I need to fast before the test?
No, fasting is not required.
How long does it take to get the report?
Reports are delivered in 3 to 4 weeks.
What is NGS?
NGS stands for Next-Generation Sequencing, a high-throughput method for DNA analysis.
What is LGMD2M?
LGMD2M is a type of limb-girdle muscular dystrophy caused by mutations in the FKTN gene, inherited in an autosomal recessive pattern.
Why is NGS preferred for genetic testing?
NGS can analyze multiple genes simultaneously, allowing faster and more comprehensive detection of mutations.
Will I get raw data files with my report?
Yes, DNA Labs India provides raw data, FASTQ, and VCF files along with the conclusive clinical report.
Is genetic counseling included?
Yes, a genetic counseling session is part of the test to draw a family pedigree and explain the implications.
Can this test identify carriers of LGMD2M?
Yes, the test can detect single heterozygous mutations, which may indicate a carrier status.
Are there any risks from the test?
The only risk is minor discomfort or bruising at the blood draw site.
How can I schedule a home sample collection?
You can book the test online and avail free home sample collection in major cities across India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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