GABRD Gene Epilepsy, idiopathic generalized type 10 NGS Genetic Test
Short Name: GABRD Gene Epilepsy NGS Genetic Test
Also known as: GABRD-related epilepsy genetic test, Idiopathic generalized epilepsy type 10 NGS panel, GABRD gene mutation analysis
GABRD Gene Epilepsy, idiopathic generalized type 10 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are generally available within 3 to 4 weeks after the sample reaches the laboratory and meets acceptance criteria. Urgent cases can be processed with prior request.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this NGS genetic test is to identify pathogenic variants in the GABRD gene that are associated with idiopathic generalized epilepsy type 10. Testing confirms the clinical diagnosis, informs prognosis, supports treatment decisions (including anti-seizure medication selection), and enables accurate genetic counseling for the patient and family members.
- Test Code
- 4075
- ICD Code
- G40.3
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are generally available within 3 to 4 weeks after the sample reaches the laboratory and meets acceptance criteria. Urgent cases can be processed with prior request.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No fasting is required. A clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with GABRD gene epilepsy are needed before the test.
Method: Blood draw or FTA card spot
Laboratory Analysis
A small blood sample is collected from the arm vein or a few drops of blood on an FTA card. The procedure is simple and non-invasive.
Report Delivery
There are no specific restrictions after sample collection. The sample will be transported to the laboratory at ambient temperature for FTA cards or under cold conditions for blood.
Timeline: Reports are generally available within 3 to 4 weeks after the sample reaches the laboratory and meets acceptance criteria. Urgent cases can be processed with prior request.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this NGS genetic test is to identify pathogenic variants in the GABRD gene that are associated with idiopathic generalized epilepsy type 10. Testing confirms the clinical diagnosis, informs prognosis, supports treatment decisions (including anti-seizure medication selection), and enables accurate genetic counseling for the patient and family members.
How to Prepare
- No fasting is required.
- Please bring the prescription or clinical history.
- A genetic counseling session will be conducted before the test to draw a family pedigree.
- Blood samples should be collected in an EDTA tube; FTA card samples can be taken by a simple finger prick.
- Ensure correct labeling of the patient's name and date of birth.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for GABRD-related epilepsy can provide a confirmatory diagnosis and enable early intervention, seizure management, and informed family counseling. For individuals and families with a history of idiopathic generalized epilepsy, preconception and neurological counseling are recommended."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Clotted or hemolyzed whole blood sample
- Insufficient quantity of blood or DNA
- Sample without proper labeling or consent form
- FTA card with insufficient blood spots
- Sample contaminated or exposed to extreme temperatures
Understanding Your Results
Confirms the clinical diagnosis of GABRD-related epilepsy (IGE type 10). Recommend genetic counseling, family testing, and personalized treatment planning.
Does not eliminate the possibility of GABRD gene involvement; other genetic or non-genetic causes should be considered. Further testing such as a comprehensive epilepsy panel may be recommended.
The variant cannot be classified as pathogenic or benign at this time. Additional family studies and functional evidence may be needed to clarify the clinical significance.
If you or a family member experience recurrent seizures, unexplained loss of consciousness, or involuntary movements, consult a neurologist immediately. A clinical evaluation with EEG and neuroimaging is essential. If epilepsy is suspected to be genetic in origin, ask your neurologist about GABRD gene NGS testing and genetic counseling.
Limitations
- ⚠NGS sequencing may not detect large gene deletions/duplications, repeat expansions, or variants in deep intronic/non-coding regulatory regions.
- ⚠A negative result does not completely rule out a genetic cause; other genes or acquired causes should be considered.
- ⚠The clinical significance of some variants may be uncertain (VUS), requiring further family studies.
- ⚠The test is specific to the GABRD gene and does not evaluate other epilepsy-related genes.
Risks & Considerations
- ●Minimal pain or bruising at the blood draw site
- ●Rare risk of infection or excessive bleeding
- ●No direct risks from the genetic test itself, but potential psychological implications of result disclosure
Interfering Factors
- ●Contamination of blood sample with foreign DNA
- ●DNA degradation due to improper storage or shipping
- ●Presence of maternal cell contamination in fetal samples
- ●Low DNA yield from FTA card due to insufficient sample
- ●Prior bone marrow transplantation may affect variant detection in blood
Compare With Similar Tests
| Test | GABRD Gene Epilepsy, idiopathic generalized type 10 NGS Genetic Test | GABRD Gene Single Gene NGS Test | Comprehensive Epilepsy NGS Panel | Chromosomal Microarray (CMA) | Whole Exome Sequencing (WES) |
|---|---|---|---|---|---|
| Comparison | GABRD Gene Epilepsy, idiopathic generalized type 10 NGS Genetic Test |
Frequently Asked Questions
What is the GABRD gene epilepsy condition?
How is the GABRD NGS genetic test performed?
What is the cost of the GABRD gene epilepsy NGS test in India?
How long does the test result take?
Do I need to fast before the test?
What sample types are accepted for this test?
Will I receive raw data files with the report?
What is the difference between a pathogenic variant and a VUS?
Can this test detect all causes of genetic epilepsy?
Is genetic counseling required before this test?
Will the test work for family members?
What if my sample gets rejected?
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