Skip to main content
DNA Labs India

GABRG2 Gene Epilepsy, childhood absence type 2 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

GABRG2 Gene Epilepsy, childhood absence type 2 NGS Genetic Test

Short Name: GABRG2 NGS Genetic Test

Also known as: GABRG2 Gene Mutation Analysis, Childhood Absence Epilepsy Type 2 Genetic Test, GABRG2 Epilepsy NGS Panel, Epilepsy Gene Sequencing for GABRG2

GABRG2 Gene Epilepsy, childhood absence type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are delivered in 3 to 4 weeks from the date the sample is received at the laboratory.. Free home collection in 300+ cities across India.

NGS Genetic TestChildren, Adolescents, Adults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To detect pathogenic variants in the GABRG2 gene associated with childhood absence epilepsy type 2, confirm a clinical diagnosis, guide antiseizure medication selection, and enable family risk assessment.

Test Code
4064
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Reports are delivered in 3 to 4 weeks from the date the sample is received at the laboratory.
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No special preparation is required. A valid doctor’s referral is recommended. Please provide clinical history, EEG/MRI reports, and family pedigree information to the laboratory before sample collection.

Method: Peripheral blood draw / FTA card spot / DNA sample submission

Step 2

Laboratory Analysis

Blood sample will be collected by a trained phlebotomist using aseptic technique. For FTA card collection, a drop of blood from a finger prick will be applied to the card.

Step 3

Report Delivery

The sample should be transported to the laboratory within 24 hours at room temperature. The FTA card should be placed in a protective pouch.

Timeline: Reports are delivered in 3 to 4 weeks from the date the sample is received at the laboratory.

Patient Instructions

1
Before the Test:A formal referral from a neurologist is helpful but not mandatory. Patients should bring previous EEG, MRI, and any relevant clinical reports. A genetic counseling session is recommended to discuss the purpose, benefits, and limitations of the test.
2
During the Test:A small sample of blood will be drawn from a vein in your arm or a drop of blood will be placed on an FTA card. The process takes only a few minutes. There is no fasting requirement.
3
After the Test:No downtime is needed. You may resume daily activities immediately. The sample will be sent to the laboratory for NGS analysis. Results will be available in 3 to 4 weeks.

About This Test

Who Should Get This Test

To detect pathogenic variants in the GABRG2 gene associated with childhood absence epilepsy type 2, confirm a clinical diagnosis, guide antiseizure medication selection, and enable family risk assessment.

How to Prepare

  • Blood sample should be collected in an EDTA vacutainer and mixed gently.
  • FTA card should be completely dried before placing in the protective pouch.
  • Label the sample with patient name, date of birth, and collection date.
  • Send the sample in a leak-proof biohazard bag with the test requisition form.
  • For extracted DNA, provide concentration and purity details if available.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early molecular confirmation of GABRG2 variants helps guide personalized antiseizure therapy and enables accurate genetic counseling for the family."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs per laboratory protocol
ContainerEDTA Vacutainer / FTA Card / DNA Elution Tube
Collection MethodPeripheral blood draw / FTA card spot / DNA sample submission

Sample Stability

Blood in EDTA: 24 hours at room temperature, 72 hours at 2-8°C.
FTA card: Stable for several weeks at room temperature.
Extracted DNA: Stable for 6 months at -20°C if stored properly.
Sample Rejection Criteria:
  • Clotted or haemolyzed blood samples
  • Mislabelled specimens or missing requisition form
  • Samples received in formalin or unknown preservatives
  • Samples with insufficient quantity or poor DNA quality

Understanding Your Results

Genetic test results should always be interpreted in the context of clinical findings, EEG data, and family history. A positive result confirms the presence of a pathogenic variant in GABRG2, while a negative result does not exclude a diagnosis of childhood absence epilepsy.
📊

Positive (Pathogenic/Likely Pathogenic variant)

Confirms a genetic cause of childhood absence epilepsy type 2. Helps guide treatment, prognosis, and family screening.

📊

Negative (No pathogenic variant)

No clinically significant GABRG2 variant was identified. Other genes or non-genetic causes may be considered.

📊

Variant of Uncertain Significance (VUS)

A DNA change was found but its clinical significance is unclear. Additional testing of family members may help clarify.

⚠️ When to Consult a Doctor:

Consult a neurologist or clinical geneticist if seizures recur, if symptoms change, if the genetic report identifies a pathogenic variant, or if you need guidance on treatment options and family planning.

Limitations

  • ⚠This test does not detect all genetic causes of childhood absence epilepsy.
  • ⚠Large structural rearrangements, trinucleotide repeat expansions, or mitochondrial genome variants may not be identified.
  • ⚠Variants of uncertain significance may be reported, requiring further family segregation studies.
  • ⚠A negative result does not exclude a genetic cause.
  • ⚠Predictive testing of asymptomatic family members requires prior informed consent and genetic counseling.

Risks & Considerations

  • ●Mild pain or bruising at the blood collection site
  • ●Lightheadedness or fainting during blood draw
  • ●No significant risks for FTA card finger prick

Interfering Factors

  • ●Maternal cell contamination in fetal or cord blood samples
  • ●Sample degradation due to improper storage or transit
  • ●Incomplete clinical information affecting variant interpretation
  • ●Variants in regulatory or non-coding regions not covered by standard NGS
  • ●Gene variants causing mosaicism may be present below the detection threshold

Compare With Similar Tests

TestGABRG2 Gene Epilepsy, childhood absence type 2 NGS Genetic Test
ComparisonGABRG2 Gene Epilepsy, childhood absence type 2 NGS Genetic Test

Frequently Asked Questions

What is the GABRG2 gene epilepsy childhood absence type 2 NGS genetic test?
It is a next-generation sequencing-based test that analyzes the GABRG2 gene to identify variants associated with childhood absence epilepsy type 2.
What is the cost of this test at DNA Labs India?
The cost of the GABRG2 gene NGS genetic test is INR 20,000, which includes free home sample collection and the clinical report.
Which sample is required for the GABRG2 gene test?
The test can be performed on blood, extracted DNA, or a single drop of blood placed on an FTA card.
Is fasting required for this genetic test?
No, fasting is not required for this test.
Who should undergo this test?
Children or adults with suspected absence seizures, staring spells, or a family history of genetic epilepsy may benefit from this test.
What is the turnaround time for the GABRG2 gene NGS test?
The reports are generally available within 3 to 4 weeks after the sample is received at the laboratory.
Will I receive raw data files?
Yes, DNA Labs India provides Raw Data, FASTQ, and VCF files along with the conclusive clinical report, ensuring full transparency.
Is the home sample collection available across India?
Yes, free home sample collection is available for online bookings in more than 250 cities across India.
How is the test performed?
DNA is extracted from the sample and the GABRG2 gene is sequenced using next-generation sequencing technology to identify disease-causing variants.
What does a positive result mean?
A positive result means a pathogenic or likely pathogenic variant in the GABRG2 gene has been identified, which can help confirm the diagnosis and guide management.
What does a negative result mean?
A negative result means no clinically significant GABRG2 variants were found. It does not completely exclude a genetic cause and other genes may need to be evaluated.
Is genetic counseling recommended?
Yes, genetic counseling is strongly recommended before and after the test to understand inheritance, implications for family members, and reproductive options.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Angelman Syndrome Test

₹10,000

Duchenne / Becker Muscular Dystrophy (DMD / BMD) Gene Mutation Test

₹14,000

Episodic Ataxia Type 1 Hotspot Test

₹11,500

Episodic Ataxia Comprehensive Profile Hotspot Test

₹16,000

Megalencephalic Leukoencephalopathy with Subcortical Cysts Van Der Knaap and Nalband MLC Gene Hotspot Mutation Test

₹7,500

Analyzer 18 SMA 18 Test Panel

₹1,755
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.