GBS Library Preparation Test
Short Name: GBS Library Prep
Also known as: GBS Library Prep, Guillain-Barré Syndrome Genetic Library Preparation
GBS Library Preparation Test test available at DNA Labs India for ₹115,000. Uses Next-Generation Sequencing (NGS), Library Preparation on Extracted DNA samples. Results in Reports are delivered within 10 days from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of GBS Library Preparation is to generate a high-quality genomic library from patient DNA, enabling comprehensive sequencing to identify genetic variants associated with Guillain-Barré Syndrome susceptibility, severity, and response to therapy. This service is essential for researchers and clinicians aiming to explore the genetic architecture of GBS, potentially leading to better diagnostic markers and targeted interventions.
- Test Code
- 6369
- CPT Code
- NA
- ICD Code
- G61.0
- Price
- ₹115,000
- Sample Type
- Extracted DNA
- Result Time
- Reports are delivered within 10 days from sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS), Library Preparation
Sample Collection
No special preparation is required. However, if providing a blood sample, inform your doctor about any medications you are taking.
Method: Blood sample or extracted DNA submission
Laboratory Analysis
A blood sample will be collected by a trained phlebotomist. If you are submitting extracted DNA, ensure it is properly labeled and stored.
Report Delivery
No specific aftercare is needed. You can resume normal activities immediately.
Timeline: Reports are delivered within 10 days from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of GBS Library Preparation is to generate a high-quality genomic library from patient DNA, enabling comprehensive sequencing to identify genetic variants associated with Guillain-Barré Syndrome susceptibility, severity, and response to therapy. This service is essential for researchers and clinicians aiming to explore the genetic architecture of GBS, potentially leading to better diagnostic markers and targeted interventions.
How to Prepare
- Use EDTA or citrate tube for blood collection.
- For extracted DNA, use a DNA LoBind tube and store at -20°C.
- Label the sample with patient ID and date of collection.
- Transport samples on dry ice if shipping.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"GBS is a post-infectious autoimmune neuropathy. Genetic library preparation aids in identifying susceptibility variants and guiding immunotherapy."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed blood samples
- Insufficient DNA quantity (< 1 µg)
- DNA with A260/280 < 1.5
- Improperly labeled samples
Understanding Your Results
Pathogenic variants in immune-related genes
Increased susceptibility to autoimmune neuropathies
Variants of uncertain significance
Further research or family studies may be needed
No significant variants
Genetic predisposition not identified; other factors may be involved
Consult your neurologist or genetic counselor to discuss the implications of your results and potential management strategies.
Limitations
- ⚠This test is not diagnostic for GBS; clinical correlation is required.
- ⚠Genetic variants identified may not have established clinical significance.
- ⚠The test does not cover all possible genetic markers.
- ⚠Results should be interpreted by a qualified geneticist.
Risks & Considerations
- ●Minimal risk of bruising at blood draw site
- ●No significant risks associated with DNA testing
Interfering Factors
- ●Degraded DNA samples
- ●Contamination with RNA or proteins
- ●Insufficient DNA quantity
- ●Presence of PCR inhibitors
- ●Improper storage conditions
Compare With Similar Tests
| Test | GBS Library Preparation | Whole Exome Sequencing | Targeted Gene Panel |
|---|---|---|---|
| Comparison | GBS Library Preparation | GBS Library Preparation focuses on targeted regions, while WES covers all coding regions. GBS prep is more cost-effective for specific research. | GBS Library Preparation is broader than a targeted panel, allowing discovery of novel variants. |
Frequently Asked Questions
What is GBS Library Preparation?
What is the cost of GBS Library Preparation?
What sample is required?
Is fasting required?
How long does it take to get results?
Is home sample collection available?
What is the turnaround time?
Can this test diagnose GBS?
What technology is used?
Is the test NABL accredited?
Can I submit my own extracted DNA?
Are there any additional charges?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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