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GNAL Gene DYT25 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

GNAL Gene DYT25 NGS Genetic Test

Short Name: GNAL DYT25 Test

Also known as: GNAL Gene Mutation Test, DYT25 Genetic Test, NGS Test for Dystonia

GNAL Gene DYT25 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose movement disorders caused by mutations in the GNAL gene, such as DYT25 dystonia, and to assist in genetic counseling and treatment planning.

Test Code
1588
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Inform the healthcare provider about any medications or medical conditions.

Method: Venipuncture for blood, or saliva collection

Step 2

Laboratory Analysis

Blood sample will be drawn from a vein or saliva collected as per instructions.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Keep the area clean.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Consult with a genetic counselor or neurologist to determine if this test is appropriate based on symptoms and family history.
2
During the Test:Sample collection is quick and minimally invasive, typically involving a blood draw or saliva sample.
3
After the Test:Results will be interpreted by a geneticist and reported to your physician for further discussion and management.

About This Test

Who Should Get This Test

To diagnose movement disorders caused by mutations in the GNAL gene, such as DYT25 dystonia, and to assist in genetic counseling and treatment planning.

How to Prepare

  • Ensure proper identification
  • Use sterile equipment
  • Label samples correctly
  • Transport samples at appropriate temperature

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This genetic test is essential for identifying mutations in the GNAL gene, which can help in the early diagnosis and management of dystonia and related movement disorders."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs required for NGS analysis
ContainerVacutainer tube for blood, or FTA card for blood drop
Collection MethodVenipuncture for blood, or saliva collection

Sample Stability

Blood samples stable for 48 hours at 2-8°C
Extracted DNA stable for longer periods
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated samples
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of mutations in the GNAL gene. A positive result confirms genetic predisposition to DYT25 dystonia.
📊

Normal result, but clinical correlation needed

📊

Confirms diagnosis of GNAL-related dystonia, recommend genetic counseling

⚠️ When to Consult a Doctor:

If you experience symptoms of dystonia such as involuntary movements or stiffness, or if you have a family history of the condition. After receiving test results, consult a neurologist or geneticist for further management.

Limitations

  • May not detect all genetic variants
  • Results should be correlated with clinical findings
  • Does not rule out other causes of dystonia

Risks & Considerations

  • Minor bruising at the blood draw site
  • Rare risk of infection
  • Emotional impact of genetic test results

Interfering Factors

  • Sample contamination
  • Degraded DNA
  • Improper sample collection

Compare With Similar Tests

TestGNAL Gene DYT25 NGS Genetic TestTOR1A Gene DYT1 NGS Genetic TestTHAP1 Gene DYT6 NGS Genetic TestGeneral Dystonia Genetic PanelNeurological Disorder Genetic Test PanelMitochondrial DNA Sequencing for Movement Disorders
ComparisonGNAL Gene DYT25 NGS Genetic TestTests for a different dystonia gene associated with early-onset torsion dystoniaIdentifies mutations in the THAP1 gene linked to DYT6 dystoniaComprehensive panel screening multiple dystonia-related genesBroad panel for various neurological conditions including dystoniaTests for mitochondrial mutations that can cause movement disorders

Frequently Asked Questions

What is the GNAL Gene DYT25 NGS Genetic Test?
It is a genetic test that uses Next Generation Sequencing to detect mutations in the GNAL gene, associated with DYT25 dystonia and movement disorders.
What are the symptoms of GNAL-related dystonia?
Symptoms include involuntary muscle movements, tremors, stiffness, difficulty with fine motor skills, and balance and coordination problems.
How is the test performed?
A blood or saliva sample is collected and analyzed in the laboratory using NGS technology to identify genetic mutations.
What is the cost of the GNAL Gene DYT25 NGS Genetic Test?
The test costs INR 20000 at DNA Labs India, including sample collection and analysis.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What sample is required for the test?
The test requires blood, extracted DNA, or one drop of blood on an FTA card.
Do I need to fast before the test?
No, fasting is not required for this genetic test.
What do the results mean?
Results indicate whether pathogenic mutations in the GNAL gene are detected, which can confirm a diagnosis of dystonia and guide treatment.
Can the test detect all mutations in the GNAL gene?
The test is comprehensive but may not detect all possible genetic variants; clinical correlation is recommended.
Who should consider this test?
Individuals with symptoms of dystonia, family history of movement disorders, or unexplained neurological issues should consider this test.
How accurate is the test?
The test uses advanced NGS technology for high accuracy, but results should be interpreted by a healthcare professional in the context of clinical findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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