GRIN2A Gene Epilepsy with neurodevelopmental defects NGS Genetic Test
Short Name: GRIN2A NGS Test
Also known as: GRIN2A-related epilepsy genetic test, GRIN2A gene sequencing test, Epilepsy neurodevelopmental defects NGS panel
GRIN2A Gene Epilepsy with neurodevelopmental defects NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks after sample submission. Occasional delays may occur due to repeat testing or technical issues.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the GRIN2A gene that are associated with epilepsy and neurodevelopmental defects. Early genetic diagnosis helps in personalized treatment planning, prognostication, and genetic counseling for affected families.
- Test Code
- 4062
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks after sample submission. Occasional delays may occur due to repeat testing or technical issues.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation is required. However, a clinical history and genetic counseling session is recommended. Please bring any prior medical reports or imaging records.
Method: Peripheral blood draw or FTA card blood spot
Laboratory Analysis
A blood sample is drawn by a trained phlebotomist in an EDTA tube. Alternatively, a few drops of blood can be applied on an FTA card for convenience.
Report Delivery
There are no restrictions after sample collection. The sample is transported to the laboratory at ambient temperature. You may return to your normal activities.
Timeline: 3 to 4 weeks after sample submission. Occasional delays may occur due to repeat testing or technical issues.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the GRIN2A gene that are associated with epilepsy and neurodevelopmental defects. Early genetic diagnosis helps in personalized treatment planning, prognostication, and genetic counseling for affected families.
How to Prepare
- Collect 2-3 ml blood in an EDTA vacutainer
- For FTA card, apply one drop of blood on each marked circle and allow to air dry
- Label the sample with patient's full name, date of birth, and collection date
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"A detailed family history and genetic counseling are essential for accurate interpretation of GRIN2A gene variants and reproductive risk assessment."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Clotted or hemolyzed blood sample
- Improperly labeled sample
- Sample received more than 5 days after collection
Understanding Your Results
Pathogenic variant identified
The variant is associated with GRIN2A-related epilepsy. Genetic counseling and familial testing are recommended.
Variant of uncertain significance (VUS)
Further studies may be needed to clarify the clinical significance. Consider segregation analysis in family members.
No pathogenic variant detected
No clinically significant mutation found in the GRIN2A gene. A broader epilepsy gene panel may be considered.
If you receive a positive result or a VUS, it is recommended to consult a neurologist and a clinical geneticist for further management, treatment planning, and family counseling.
Limitations
- ⚠NGS may not detect large gene rearrangements, repeat expansions, or deep intronic variants
- ⚠Negative results do not rule out a genetic cause of epilepsy
- ⚠Variants of uncertain significance may require additional familial testing
Risks & Considerations
- ●Slight pain or bruising at the blood draw site
- ●Rare risk of infection at needle site
- ●Psychological impact of results
Interfering Factors
- ●Bone marrow transplant from another person may alter DNA test results
- ●Recent blood transfusion can affect DNA extraction and analysis
- ●Sample contamination with microbial DNA
Compare With Similar Tests
| Test | GRIN2A Gene Epilepsy with neurodevelopmental defects NGS Genetic Test | ||
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| Comparison | GRIN2A Gene Epilepsy with neurodevelopmental defects NGS Genetic Test |
Frequently Asked Questions
What is the GRIN2A gene epilepsy with neurodevelopmental defects NGS genetic test?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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