GRM7 Gene Autism Spectrum/Hyperactivity/Bipolar Disorder, GRM7 Related NGS Genetic Test
Short Name: GRM7 NGS Genetic Test
GRM7 Gene Autism Spectrum/Hyperactivity/Bipolar Disorder, GRM7 Related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS), Sanger confirmation if required on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect sequence variants in the GRM7 gene that may contribute to autism spectrum disorder, hyperactivity, or bipolar disorder. It helps in confirming a diagnosis, guiding treatment and management decisions, and enabling genetic counselling.
- Test Code
- 3901
- ICD Code
- F84.0, F90.0, F31
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Results are typically available within 3 to 4 weeks from sample receipt.
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS), Sanger confirmation if required
Sample Collection
No special preparation is required. Fasting is not necessary. Clinical history and genetic counselling are recommended before testing.
Method: Venipuncture / FTA card blood spot
Laboratory Analysis
A trained phlebotomist collects blood or a blood spot on the FTA card. The process is minimally invasive and takes a few minutes.
Report Delivery
No post-collection restrictions. The sample is transported to the laboratory at ambient room temperature unless otherwise specified.
Timeline: Results are typically available within 3 to 4 weeks from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect sequence variants in the GRM7 gene that may contribute to autism spectrum disorder, hyperactivity, or bipolar disorder. It helps in confirming a diagnosis, guiding treatment and management decisions, and enabling genetic counselling.
How to Prepare
- Avoid any form of fasting before the test.
- If on anticoagulant therapy, inform the healthcare provider prior to blood collection.
- Ensure the FTA card is completely dried before packaging if using blood spot.
- Label the sample correctly with name, date, and time of collection.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic evaluation of GRM7 gene variants can support clinical diagnosis and management of autism spectrum disorder, hyperactivity, and bipolar disorder. Combining NGS data with careful clinical correlation is essential for accurate interpretation and counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolysed blood sample
- Clotted sample when blood is required
- Improperly labelled sample
- Frozen whole blood (unless frozen DNA is provided)
Understanding Your Results
Pathogenic variant detected
Indicates a strong risk for GRM7-related disorder. Clinical correlation and management planning are recommended.
Likely pathogenic variant detected
Suggests a high likelihood of disease association. Additional evidence may be needed to confirm.
Variant of uncertain significance (VUS)
The variant’s clinical significance is not yet clear. Family studies or further genetic testing may be needed.
No pathogenic variants detected
No actionable GRM7 variants were identified. The condition might be due to other genetic or non-genetic factors.
If the test result shows a pathogenic or likely pathogenic variant, or if you have persistent symptoms of autism, hyperactivity, or mood instability, you should consult with your referring physician or a clinical geneticist for detailed counselling and management.
Limitations
- ⚠This test only analyses GRM7 gene variants and does not cover other genes associated with autism, hyperactivity, or bipolar disorder.
- ⚠Regulatory regions and deep intronic mutations may not be covered.
- ⚠Copy number variants or structural variants may not be detected by standard NGS sequencing.
- ⚠Interpretation of variants of uncertain significance (VUS) may require further family studies.
- ⚠A negative result does not exclude genetic or environmental causes of the condition.
Risks & Considerations
- ●No significant physical risks associated with blood draw other than slight bruising or pain at the puncture site.
- ●Psychological impact of potential genetic finding.
- ●Possibility of genetic discrimination if result is disclosed improperly.
Interfering Factors
- ●Low-quality DNA or degraded sample
- ●Contamination of sample during collection
- ●Presence of haematological malignancies causing clonal haematopoiesis
- ●Variants in pseudogenes or homologous regions may affect detection
Compare With Similar Tests
| Test | GRM7 Gene Autism Spectrum/Hyperactivity/Bipolar Disorder, GRM7 Related NGS Genetic Test | Chromosomal Microarray (CMA) | Whole Exome Sequencing (WES) | Autism NGS Panel | Bipolar Disorder Genetic Test |
|---|---|---|---|---|---|
| Comparison | GRM7 Gene Autism Spectrum/Hyperactivity/Bipolar Disorder, GRM7 Related NGS Genetic Test |
Frequently Asked Questions
What is the GRM7 gene?
What does the GRM7 NGS genetic test include?
What is the cost of the GRM7 NGS genetic test?
What sample types are accepted for this test?
Is fasting required before the test?
How long does it take to receive the results?
What is a pathogenic variant in the GRM7 gene?
What does a negative GRM7 test result mean?
Can this test be performed on children?
Can I get the raw data files with this test?
Are there any risks associated with this test?
Is genetic counselling available?
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