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Growth Hormone Releasing Hormone (GHRH) Test

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Growth Hormone Releasing Hormone (GHRH) Test

Short Name: GHRH Test

Also known as: GHRH Blood Test, Growth Hormone Releasing Hormone Assay, GHRH Serum Test

Growth Hormone Releasing Hormone (GHRH) Test test available at DNA Labs India for ₹35,000. Uses Extraction, Radioimmunoassay on 3 mL (1 mL min.) serum from 1 Red Top (No Additive) tube. Do not use SST gel barrier tubes. Separate serum into a sterile screw capped vial and freeze immediately. Ship frozen. DO NOT THAW. samples. Results in Sample must reach the laboratory by the 7th of the month; report is typically available after 2-3 weeks.. Free home collection in 300+ cities across India.

EndocrinologistAll age groups🏠 Home Collection

🩺 Medically Reviewed By

Overview

This test measures the level of growth hormone releasing hormone (GHRH) in the blood. It aids in evaluating disorders of the pituitary gland, particularly when growth hormone deficiency or excess is suspected. It may be used to identify rare GHRH hypersecretion by peripheral or endocrine tumors in patients with acromegaly.

Test Code
3469
Price
₹35,000
Sample Type
3 mL (1 mL min.) serum from 1 Red Top (No Additive) tube. Do not use SST gel barrier tubes. Separate serum into a sterile screw capped vial and freeze immediately. Ship frozen. DO NOT THAW.
Result Time
Sample must reach the laboratory by the 7th of the month; report is typically available after 2-3 weeks.
Fasting Required
Yes (8 hours)
Method
Extraction, Radioimmunoassay
Step 1

Sample Collection

Fast for at least 8 hours and avoid all medications that may influence pituitary secretion unless instructed otherwise. Duly filled Test Send Out Consent Form (Form 35) is mandatory.

Method: Venipuncture

Step 2

Laboratory Analysis

A healthcare professional will collect 3 mL (minimum 1 mL) of blood from a vein into a red top no-additive tube. SST gel barrier tubes must not be used.

Step 3

Report Delivery

The serum must be separated into a sterile screw capped vial and frozen immediately. The sample should be shipped frozen and must not be thawed.

Timeline: Sample must reach the laboratory by the 7th of the month; report is typically available after 2-3 weeks.

Patient Instructions

1
Before the Test:Fast for at least 8 hours and avoid medications that may influence pituitary secretion unless instructed otherwise. Duly filled Test Send Out Consent Form (Form 35) is mandatory.
2
During the Test:A healthcare professional will collect 3 mL (minimum 1 mL) of blood from a vein into a red top no-additive tube. SST gel barrier tubes must not be used.
3
After the Test:The serum must be separated into a sterile screw capped vial and frozen immediately. The sample should be shipped frozen and must not be thawed.

About This Test

Who Should Get This Test

This test measures the level of growth hormone releasing hormone (GHRH) in the blood. It aids in evaluating disorders of the pituitary gland, particularly when growth hormone deficiency or excess is suspected. It may be used to identify rare GHRH hypersecretion by peripheral or endocrine tumors in patients with acromegaly.

How to Prepare

  • Schedule the test after an overnight fast of at least 8 hours
  • Avoid medications that may influence pituitary secretion as advised by your doctor
  • A single venipuncture is used to collect 3 mL of blood
  • Do not use SST gel barrier tubes; use a red top no-additive tube
  • Separate serum into a sterile screw capped vial and freeze immediately
  • Fill and send the mandatory Test Send Out Consent Form (Form 35)

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"GHRH testing is a specialized second-line investigation. In suspected acromegaly, IGF-1 and growth hormone suppression tests are usually first line, but ectopic GHRH-producing tumors are rare and should be considered when growth hormone excess is not explained by pituitary imaging. This test should be done after a complete endocrine evaluation and medication washout as advised."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample Type3 mL (1 mL min.) serum from 1 Red Top (No Additive) tube. Do not use SST gel barrier tubes. Separate serum into a sterile screw capped vial and freeze immediately. Ship frozen. DO NOT THAW.
Sample Volume3 mL (1 mL min.)
ContainerRed Top (No Additive) tube; separate serum into a sterile screw capped vial and freeze immediately
Collection MethodVenipuncture

Sample Stability

Room Temperature: NA
Refrigerator: NA
Frozen: 2 months
Sample Rejection Criteria:
  • SST gel barrier tube used
  • Thawed sample
  • Insufficient serum volume (<1 mL)
  • Missing Test Send Out Consent Form (Form 35)

Understanding Your Results

GHRH results should be interpreted by an endocrinologist in conjunction with clinical signs, growth hormone levels, and imaging. A single value should not be used in isolation.
Elevated GHRH with clinical GH excess may indicate ectopic GHRH production and requires tumor localization
Normal or low GHRH with GH excess suggests pituitary adenoma until proven otherwise
Low GHRH in a child with short stature or delayed growth may support further endocrine evaluation for growth hormone deficiency
All results must be interpreted by an endocrinologist with paired GH/IGF-1 and imaging as applicable
⚠️ When to Consult a Doctor:

Consult a doctor if you or your child have slow growth, delayed puberty, short stature, decreased muscle mass, increased body fat, low bone density, fatigue, memory problems, or symptoms of acromegaly such as enlarged hands and feet, coarse facial features, or joint pain.

Limitations

  • GHRH hypersecretion by peripheral tumors is rare; most acromegaly is due to pituitary growth hormone excess
  • A single GHRH level may not fully assess growth hormone dynamics
  • Specialized sample handling is required for reliable results

Risks & Considerations

  • Mild pain or bruising at the venipuncture site
  • Lightheadedness
  • Bleeding at the puncture site
  • Infection at the puncture site is rare

Interfering Factors

  • Medications that influence pituitary secretion
  • Use of SST gel barrier tubes
  • Improper sample storage or thawing
  • Recent hormonal therapy

Frequently Asked Questions

What is the GHRH test?
The Growth Hormone Releasing Hormone (GHRH) test measures the level of GHRH in the blood. GHRH is a hormone that stimulates the release of growth hormone from the pituitary gland.
Why is the GHRH test done?
The test is done to help diagnose conditions related to growth hormone deficiency or excess, including rare cases of acromegaly caused by GHRH hypersecretion from peripheral or endocrine tumors.
What is the cost of the GHRH test at DNA Labs India?
The cost of the GHRH test at DNA Labs India is INR 35,000.
Is fasting required for the GHRH test?
Yes, fasting for at least 8 hours is required before giving the sample.
What sample is required for the GHRH test?
A 3 mL (minimum 1 mL) serum sample is required. It should be collected in a red top no-additive tube. SST gel barrier tubes should not be used.
How is the GHRH sample processed?
Serum should be separated into a sterile screw capped vial and frozen immediately. The sample must be shipped frozen and should not be thawed.
What is the turnaround time for the GHRH test?
The sample must reach the laboratory by the 7th of the month, and the report is typically available after 2-3 weeks.
Is home sample collection available for the GHRH test?
Yes, DNA Labs India offers free home sample collection for online bookings of the GHRH test across India.
What are the symptoms of growth hormone deficiency?
In children, symptoms may include delayed puberty, slow growth rate, short stature, delayed tooth development, and delayed bone age. In adults, symptoms may include decreased muscle mass, increased body fat, decreased bone density, low energy, and impaired memory or concentration.
What are the symptoms of growth hormone excess?
Growth hormone excess may occur in acromegaly and can cause enlarged hands and feet, coarse facial features, thickening of the skin, enlarged organs, and joint pain or stiffness.
What medications should be avoided before the GHRH test?
Patients should avoid all medications that may influence pituitary secretion as advised by the doctor. A duly filled Test Send Out Consent Form (Form 35) is mandatory.
How will I receive my GHRH test report?
Reports are delivered through the online portal, email, or WhatsApp after testing is complete and results are validated.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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