HLA A, B, DRB1 [High Resolution] Test
Short Name: HLA High Resolution
Also known as: Human Leukocyte Antigen Testing, HLA Typing, High-Resolution HLA Test
HLA A, B, DRB1 [High Resolution] Test test available at DNA Labs India for ₹15,000. Uses Next-Generation Sequencing (NGS) on Peripheral blood or Buccal swabs (4-6 no.) samples. Results in 10-12 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The primary purpose of the HLA A, B, DRB1 High Resolution test is to determine genetic compatibility between donors and recipients for transplants, reducing the risk of rejection. Additionally, it helps diagnose autoimmune diseases by identifying specific HLA variations associated with immune system dysfunction, guiding treatment plans and management strategies.
- Test Code
- 3042
- Price
- ₹15,000
- Sample Type
- Peripheral blood or Buccal swabs (4-6 no.)
- Result Time
- 10-12 days
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation is required, but inform your healthcare provider about any medications or recent transfusions.
Method: Venipuncture for blood, Swab for buccal samples
Laboratory Analysis
A small blood sample will be drawn from a vein in your arm, or buccal swabs will be taken from the inside of your cheek.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Resume normal activities immediately.
Timeline: 10-12 days
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the HLA A, B, DRB1 High Resolution test is to determine genetic compatibility between donors and recipients for transplants, reducing the risk of rejection. Additionally, it helps diagnose autoimmune diseases by identifying specific HLA variations associated with immune system dysfunction, guiding treatment plans and management strategies.
How to Prepare
- Ensure proper identification of the patient
- Use sterile collection equipment
- Label samples accurately with patient details
- Transport samples at ambient or cool temperature as specified
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"HLA testing is crucial for diagnosing autoimmune conditions and ensuring successful transplant outcomes by assessing genetic compatibility."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrectly labeled or contaminated samples
Understanding Your Results
High compatibility
Low risk of transplant rejection, suitable for proceeding with transplant.
Low compatibility
High risk of rejection, may require alternative donors or additional therapies.
Presence of disease-associated alleles
Increased likelihood of autoimmune condition, correlate with clinical symptoms for diagnosis.
Normal variants
No significant associations found, but clinical evaluation is recommended if symptoms persist.
Consult a doctor if you experience symptoms like joint pain, fatigue, or unexplained weight loss, or if you are undergoing transplant evaluation. Discuss HLA testing results with your healthcare provider for personalized advice.
Limitations
- ⚠May not detect all rare genetic variations
- ⚠Requires specialized laboratory equipment and expertise
- ⚠Results interpretation depends on clinical context
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection or dizziness
- ●No significant risks associated with buccal swabs
Interfering Factors
- ●Recent blood transfusion may affect results
- ●Sample contamination or improper storage
- ●Certain medications influencing immune response
Compare With Similar Tests
| Test | HLA A, B, DRB1 [High Resolution] | HLA Low Resolution | HLA DQ Test | HLA DP Test | Autoimmune Panel |
|---|---|---|---|---|---|
| Comparison | HLA A, B, DRB1 [High Resolution] |
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