HLA - DR5 (DRB1*11/12) Test
Short Name: HLA-DR5 (DRB1*11/12) Test
Also known as: HLA-DR5 (DRB1*11/12) Genotyping, HLA-DRB1*11/12 Typing, HLA-DR5 Allele Detection
HLA - DR5 (DRB1*11/12) Test test available at DNA Labs India for ₹6,000. Uses Reverse SSOP - Luminex on Whole Blood samples. Results in Reports are usually available within 10-12 days from sample receipt at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of HLA-DR5 (DRB1*11/12) genotyping is to detect the presence of HLA-DRB1*11 or HLA-DRB1*12 alleles in individuals who may be at increased risk for certain autoimmune diseases. It may be used to support clinical evaluation, aid risk assessment, and guide further workup when autoimmune disease is suspected.
- Test Code
- 3480
- Price
- ₹6,000
- Sample Type
- Whole Blood
- Result Time
- Reports are usually available within 10-12 days from sample receipt at the laboratory.
- Fasting Required
- No
- Method
- Reverse SSOP - Luminex
Sample Collection
No special preparation or fasting is required. Inform your physician about recent blood transfusions or stem cell transplant.
Method: Venipuncture
Laboratory Analysis
A healthcare professional will collect a blood sample from a vein in your arm. You may feel a brief pinch or mild discomfort.
Report Delivery
You can resume normal activities immediately. Keep the collection site clean and dry.
Timeline: Reports are usually available within 10-12 days from sample receipt at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of HLA-DR5 (DRB1*11/12) genotyping is to detect the presence of HLA-DRB1*11 or HLA-DRB1*12 alleles in individuals who may be at increased risk for certain autoimmune diseases. It may be used to support clinical evaluation, aid risk assessment, and guide further workup when autoimmune disease is suspected.
How to Prepare
- Collect 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube.
- Mix gently by inversion; do not shake the sample.
- Ship refrigerated. DO NOT FREEZE.
- Label the sample correctly and send to the laboratory as soon as possible.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"HLA-DR5 genotyping helps identify individuals at increased genetic risk for certain autoimmune diseases. It is not a diagnostic test for any disease. Results should be interpreted along with clinical symptoms, family history, and other laboratory workup."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Frozen sample
- Inadequate sample volume
- Haemolysed or clotted sample
- Improper container
- Unlabelled or mislabelled sample
Understanding Your Results
HLA-DRB1*11 or *12 Detected
Increased genetic susceptibility to certain autoimmune diseases. This association is not diagnostic and requires clinical correlation.
HLA-DRB1*11 and *12 Not Detected
The tested alleles were not identified. Risk may still be influenced by other genetic and environmental factors.
Consult a physician if you have symptoms such as joint pain, fatigue, or inflammation, or a family history of autoimmune disease. A positive result should be discussed with a rheumatologist or internal medicine specialist.
Limitations
- ⚠A negative result does not rule out autoimmune disease.
- ⚠A positive result indicates increased genetic risk only and cannot predict disease development.
- ⚠This test detects only HLA-DRB1*11 and HLA-DRB1*12 alleles; it does not evaluate all HLA alleles or other genetic and environmental risk factors.
- ⚠Results must be interpreted with clinical symptoms and other laboratory tests.
Risks & Considerations
- ●Mild pain or bruising at needle site
- ●Lightheadedness
- ●Rare infection at puncture site
Interfering Factors
- ●Recent blood transfusion may affect genotyping results
- ●Haematopoietic stem cell transplant may alter genetic profile in blood
- ●Freezing the sample can cause DNA degradation
- ●Insufficient sample volume may lead to test failure
- ●Improper sample storage or handling
Compare With Similar Tests
| Test | HLA - DR5 (DRB1*11/12) Test | ||
|---|---|---|---|
| Comparison | HLA - DR5 (DRB1*11/12) Test |
Frequently Asked Questions
What is HLA-DR5 (DRB1*11/12)?
What are the symptoms of HLA-DR5 (DRB1*11/12)?
How is HLA-DR5 (DRB1*11/12) diagnosed?
What is the cost of HLA-DR5 (DRB1*11/12) test in India?
Is fasting required for HLA-DR5 (DRB1*11/12) test?
What sample is required for the HLA-DR5 (DRB1*11/12) test?
How long does it take to get the report?
Is home sample collection available?
Which autoimmune diseases are associated with HLA-DR5 (DRB1*11/12)?
Does a positive HLA-DR5 result mean I have an autoimmune disease?
What testing method is used?
Is a physician referral required for this test?
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