HLA Pre-Transplant Workup Panel 2 Test
Short Name: HLA Panel 2 Test
Also known as: Histocompatibility Test, HLA Typing Test
HLA Pre-Transplant Workup Panel 2 Test test available at DNA Labs India for ₹28,665. Uses Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology, Flow cytometry on Multiple blood samples: whole blood in ACD tube, serum from SST, whole blood in EDTA tube, whole blood in Sodium Heparin tube samples. Results in 10-12 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 3, 2026
Overview
To determine compatibility between organ donors and recipients by assessing HLA antigens, evaluating sensitization, and screening for alloantibodies to reduce the risk of organ rejection post-transplant.
- Test Code
- 820
- Price
- ₹28,665
- Sample Type
- Multiple blood samples: whole blood in ACD tube, serum from SST, whole blood in EDTA tube, whole blood in Sodium Heparin tube
- Result Time
- 10-12 days
- Fasting Required
- No
- Method
- Complement Dependent Cytotoxicity with DTT treatment, Reverse SSOP - Luminex, Luminex X-Map technology, Flow cytometry
Sample Collection
Collect specimen preferably 48 hours after dialysis. Doctor's prescription on letterhead with 1 photograph each of recipient and donor duly stamped AND Consent form for HLA Typing for Solid Organ Transplant (Form 33) is mandatory.
Method: Venipuncture
Laboratory Analysis
Blood samples are collected via venipuncture into specified tubes (ACD, SST, EDTA, Sodium Heparin) from both donor and recipient. Standard aseptic techniques are followed.
Report Delivery
Samples are labeled correctly and shipped at room temperature (18-22°C). Do not refrigerate or freeze. Ensure all documentation is included with the samples.
Timeline: 10-12 days
Patient Instructions
About This Test
Who Should Get This Test
To determine compatibility between organ donors and recipients by assessing HLA antigens, evaluating sensitization, and screening for alloantibodies to reduce the risk of organ rejection post-transplant.
How to Prepare
- Patient should preferably be 48 hours post-dialysis
- Provide doctor's prescription on letterhead with stamped photos of recipient and donor
- Submit signed Consent form for HLA Typing (Form 33)
- Collect blood in specified tubes: ACD, SST, EDTA, Sodium Heparin
- Ship samples at room temperature (18-22°C); do not refrigerate or freeze
- Ensure sample containers are properly labeled and sealed
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is critical in pre-transplant evaluation for kidney transplant recipients to assess HLA compatibility, reducing the risk of organ rejection and improving transplant success rates."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Missing or incomplete documentation (prescription, consent form, photos)
- Samples refrigerated or frozen
- Insufficient sample volume
- Incorrect sample type or container used
- Sample collected less than 48 hours after dialysis without justification
Understanding Your Results
High HLA match
Lower risk of organ rejection; better transplant outcome.
Low HLA match
Higher risk of rejection; may require additional immunosuppression or donor reconsideration.
Positive crossmatch
Recipient has antibodies against donor HLA; transplant may be contraindicated.
Negative crossmatch
No detectable antibodies; transplant may proceed with caution.
High Panel Reactive Antibodies (PRA)
Recipient is sensitized, increasing rejection risk; may need careful donor selection.
Consult your transplant physician immediately if you experience symptoms of organ rejection such as fever, pain over transplant site, decreased urine output, shortness of breath, or weight gain post-transplant.
Limitations
- ⚠Results are for pre-transplant evaluation only and do not guarantee transplant success
- ⚠Does not replace other clinical assessments for transplant suitability
- ⚠May not detect all rare HLA antigens
- ⚠Turnaround time is 10-12 days, which may delay urgent cases
Risks & Considerations
- ●Minimal risks associated with blood draw, such as bruising, infection, or fainting.
Interfering Factors
- ●Recent blood transfusions may affect HLA antibody levels
- ●Immunosuppressive medications can alter results
- ●Sample collection not following specified protocols
- ●Dialysis timing: specimen preferably collected 48 hours after dialysis
Frequently Asked Questions
What is the HLA Pre-Transplant Workup Panel 2 Test?
Why is this test important before a transplant?
What does the test involve?
How should I prepare for the test?
Is fasting required for this test?
What is the cost of the test?
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What are the symptoms of organ rejection after transplant?
What if the test shows a high mismatch?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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