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HTRA2 Gene PARK13 Parkinson NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

HTRA2 Gene PARK13 Parkinson NGS Genetic Test

Short Name: HTRA2 PARK13 NGS Test

Also known as: PARK13 Genetic Test, HTRA2 Mutation Test

HTRA2 Gene PARK13 Parkinson NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the HTRA2 Gene PARK13 Parkinson NGS Genetic Test is to identify mutations in the HTRA2 gene that may increase the risk of Parkinson's disease, enabling early diagnosis, family planning, and personalized medical management.

Test Code
1785
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Provide a detailed clinical history of the patient, including symptoms and family history. Undergo a genetic counseling session to draw a pedigree chart of family members affected with Parkinson's disease or related neurological disorders.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be collected via venipuncture or an alternative DNA sample as specified. The process is quick and minimally invasive.

Step 3

Report Delivery

The sample will be processed for NGS analysis. Reports will be generated and delivered within the specified turnaround time.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history assessment.
2
During the Test:Sample collection via blood draw.
3
After the Test:Report generation and delivery within 3-4 weeks.

About This Test

Who Should Get This Test

The purpose of the HTRA2 Gene PARK13 Parkinson NGS Genetic Test is to identify mutations in the HTRA2 gene that may increase the risk of Parkinson's disease, enabling early diagnosis, family planning, and personalized medical management.

How to Prepare

  • Ensure the patient has provided clinical history prior to sample collection.
  • Schedule a genetic counseling session to discuss family history and test implications.
  • Collect blood sample using standard venipuncture techniques.
  • Label the sample correctly with patient details.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for HTRA2 mutations can help identify individuals at increased risk for Parkinson's disease, enabling early monitoring and potential interventions to manage symptoms."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 ml blood
ContainerEDTA tube
Collection MethodVenipuncture

Sample Stability

Blood at ambient temperature
Extracted DNA at -20°C
Sample Rejection Criteria:
  • Insufficient sample volume
  • Hemolyzed or clotted blood sample
  • Incorrect labeling or missing patient information

Understanding Your Results

Results from the HTRA2 Gene PARK13 Parkinson NGS Genetic Test are interpreted based on the presence or absence of mutations in the HTRA2 gene. Genetic counseling is recommended to understand the implications.
📊

Positive for pathogenic mutation

Increased risk for Parkinson's disease. Clinical correlation and monitoring advised.

📊

Negative for pathogenic mutation

No mutation detected in the HTRA2 gene. Does not rule out Parkinson's disease from other causes.

📊

Variant of uncertain significance

Further testing or family studies may be needed for clarification.

⚠️ When to Consult a Doctor:

Consult a neurologist or genetic counselor if you experience Parkinson's disease symptoms, have a family history of the disease, or receive a positive genetic test result for guidance on management and next steps.

Limitations

  • ⚠This test only analyzes the HTRA2 gene and may not detect other genetic or environmental causes of Parkinson's disease.
  • ⚠Results do not confirm the presence or absence of Parkinson's disease, only genetic risk.
  • ⚠Negative results do not rule out Parkinson's disease entirely.

Risks & Considerations

  • ●Minor bruising or discomfort at the blood draw site
  • ●Rare risk of infection

Interfering Factors

  • ●Degraded DNA sample
  • ●Hemolyzed or insufficient blood sample
  • ●Contamination during sample handling

Frequently Asked Questions

What is the HTRA2 gene?
The HTRA2 gene encodes a protein involved in mitochondrial function, and mutations in this gene are associated with an increased risk of Parkinson's disease.
How is this test performed?
The test uses next-generation sequencing (NGS) technology to analyze DNA from a blood or extracted sample for mutations in the HTRA2 gene.
Who should consider this test?
Individuals with a family history of Parkinson's disease, early-onset symptoms, or those undergoing genetic counseling for neurological disorders.
What is the cost of the test?
The cost is INR 20,000, which includes home sample collection across India.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after sample collection.
Is fasting required for this test?
No, fasting is not required for the HTRA2 Gene PARK13 Parkinson NGS Genetic Test.
What samples are accepted?
Blood, extracted DNA, or one drop of blood on an FTA card are accepted sample types.
What does a positive result mean?
A positive result indicates a mutation in the HTRA2 gene, which may increase the risk of developing Parkinson's disease, but it does not confirm the disease.
Can this test diagnose Parkinson's disease?
No, this test detects genetic mutations but cannot diagnose Parkinson's disease. Diagnosis is based on clinical symptoms and medical evaluation.
Is home sample collection available?
Yes, free home sample collection is available for online bookings in many cities across India.
What are the symptoms of Parkinson's disease?
Symptoms include tremors, stiffness, difficulty with balance and coordination, slow movement, and impaired posture.
How accurate is the NGS genetic test?
The test is highly accurate due to advanced NGS technology, capable of detecting even minor mutations in the HTRA2 gene.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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