ICOS Gene Immunodeficiency common variable type 1 NGS Genetic Test
Short Name: ICOS Gene Immunodeficiency Type 1 NGS Test
Also known as: ICOS Deficiency, Common Variable Immunodeficiency due to ICOS Mutation, CVID1
ICOS Gene Immunodeficiency common variable type 1 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to diagnose Immunodeficiency Common Variable Type 1 caused by ICOS gene mutations, guide treatment decisions, and facilitate genetic counseling for affected individuals and families.
- Test Code
- 2424
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with immunodeficiency disorders.
Method: Venipuncture or finger prick
Laboratory Analysis
Blood sample is collected via venipuncture or finger prick, or extracted DNA is provided.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store sample as per instructions.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to diagnose Immunodeficiency Common Variable Type 1 caused by ICOS gene mutations, guide treatment decisions, and facilitate genetic counseling for affected individuals and families.
How to Prepare
- Fast for 8-12 hours if specified, though not required for this test.
- Avoid strenuous activity before sample collection.
- Bring identification and prescription if available.
- Inform the phlebotomist of any medications or health conditions.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for diagnosing rare immunodeficiency disorders and guiding personalized treatment plans, especially in families with a history of immune system issues."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient sample volume
- Hemolyzed or clotted samples
- Incorrect labeling
- Contaminated samples
Understanding Your Results
Positive for pathogenic mutation
Confirms diagnosis of Immunodeficiency Common Variable Type 1. Genetic counseling and treatment planning recommended.
Negative for pathogenic mutation
No mutations detected in the ICOS gene. Consider other genetic or immunological tests if symptoms persist.
Variant of uncertain significance
Further testing and clinical correlation needed. Genetic counseling advised.
Consult a doctor if you experience recurrent infections, autoimmune symptoms, or have a family history of immunodeficiency. After testing, discuss results with a geneticist or immunologist for management.
Limitations
- ⚠May not detect all types of genetic variants
- ⚠Variants of uncertain significance may be identified
- ⚠Does not rule out other immunodeficiency disorders
- ⚠Results require clinical correlation
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Rare allergic reaction to antiseptic
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Incorrect sample storage
- ●Hemolyzed blood samples
Frequently Asked Questions
What is ICOS Gene Immunodeficiency Common Variable Type 1?
What are the common symptoms of this disorder?
How is this disorder diagnosed?
What is the cost of the NGS Genetic Test in India?
What sample is required for the test?
Is fasting required before the test?
How long does it take to get the results?
What does a positive test result mean?
What treatment options are available?
Is there a cure for this disorder?
Can this test be done at home?
Why should I choose DNA Labs India for this test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.