IFNGR1 Gene Mycobacterial infection, atypical, familial disseminated NGS Genetic Test
Short Name: IFNGR1 NGS Genetic Test
Also known as: IFNGR1 Gene Test, Mycobacterial Infection Genetic Test, Atypical Mycobacterial Infection NGS Test
IFNGR1 Gene Mycobacterial infection, atypical, familial disseminated NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify genetic mutations in the IFNGR1 gene that cause susceptibility to atypical mycobacterial infections, enabling accurate diagnosis, personalized treatment, and genetic counseling for affected individuals and their families.
- Test Code
- 5059
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide clinical history of the patient and undergo a genetic counseling session to draw a pedigree chart of family members affected with mycobacterial infections.
Method: Venipuncture or Fingerstick
Laboratory Analysis
Blood sample will be collected via venipuncture or fingerstick onto an FTA card. Ensure proper labeling and handling.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Store sample at ambient room temperature if not processed immediately.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify genetic mutations in the IFNGR1 gene that cause susceptibility to atypical mycobacterial infections, enabling accurate diagnosis, personalized treatment, and genetic counseling for affected individuals and their families.
How to Prepare
- Fast for not required, but avoid heavy meals before blood draw
- Bring identification and prescription if available
- Inform the phlebotomist of any bleeding disorders or medications
- Sample can be blood, extracted DNA, or one drop on FTA card
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This NGS genetic test is essential for identifying mutations in the IFNGR1 gene, which can predispose individuals to severe and recurrent mycobacterial infections. Early diagnosis allows for targeted management and genetic counseling for affected families."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
Pathogenic Variant Detected
High risk for familial disseminated atypical mycobacterial infection. Genetic counseling and clinical management recommended.
Variant of Uncertain Significance (VUS)
Further testing and family studies may be needed. Clinical correlation is essential.
No Pathogenic Variant Detected
Low genetic risk based on current knowledge. Consider other diagnostic tests if symptoms persist.
Consult a doctor if you have recurrent mycobacterial infections, a family history of such infections, or symptoms like chronic fever, cough, skin lesions, or unexplained weight loss. Genetic counseling is advised before and after testing.
Limitations
- ⚠May not detect all possible mutations in the IFNGR1 gene or related genes
- ⚠Results require interpretation by a genetic specialist
- ⚠Does not rule out other causes of immunodeficiency
- ⚠Turnaround time may vary based on laboratory workload
Risks & Considerations
- ●Minor bruising or discomfort at the blood draw site
- ●Rare risk of infection or fainting
- ●Psychological impact of genetic results
Interfering Factors
- ●Hemolyzed or degraded DNA samples may affect test accuracy
- ●Recent blood transfusions could interfere with genetic analysis
- ●Contamination during sample collection or processing
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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