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DNA Labs India

IHC ER-PR Test

DNA Labs India | ISO 9001:2015 Certified

IHC ER-PR Test

Also known as: Estrogen Receptor IHC, Progesterone Receptor IHC, ER PR IHC

IHC ER-PR Test test available at DNA Labs India for ₹4,000. Uses Immunohistochemistry on Tissue/ Paraffin block samples. Results in 3 days. Free home collection in 300+ cities across India.

OncologyFemaleAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the IHC ER-PR test is to identify the presence of estrogen and progesterone receptors in breast cancer tissue, which helps in predicting the effectiveness of hormonal therapy and guiding treatment decisions for improved patient outcomes.

Test Code
3053
Price
₹4,000
Sample Type
Tissue/ Paraffin block
Result Time
3 days
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Consult a doctor for prescription. Prescription is not applicable for surgery, pregnancy cases, or travel abroad.

Method: Biopsy or Surgery

Step 2

Laboratory Analysis

Tissue sample is collected via biopsy or surgical procedure under sterile conditions.

Step 3

Report Delivery

Sample is preserved in formalin or as a paraffin block and sent to the laboratory for processing.

Timeline: 3 days

Patient Instructions

1
Before the Test:Obtain a doctor's prescription and ensure proper sample collection from biopsy or surgery.
2
During the Test:Tissue sample undergoes immunohistochemical staining to detect ER and PR receptors.
3
After the Test:Results are analyzed by pathologists and reported within 3 days.

About This Test

Who Should Get This Test

The purpose of the IHC ER-PR test is to identify the presence of estrogen and progesterone receptors in breast cancer tissue, which helps in predicting the effectiveness of hormonal therapy and guiding treatment decisions for improved patient outcomes.

How to Prepare

  • Ensure tissue is fixed in 10% neutral buffered formalin promptly
  • Label sample with patient details accurately
  • Transport at ambient temperature to prevent degradation

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The IHC ER-PR test is crucial for determining hormone receptor status in breast cancer, guiding personalized treatment plans and improving patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTissue/ Paraffin block
Sample VolumeAs required
ContainerTissue in 10% Neutral Buffered Formalin OR Block
Collection MethodBiopsy or Surgery

Sample Stability

Tissue in formalin stable for 24-48 hours at room temperature
Paraffin block stable for long-term storage
Sample Rejection Criteria:
  • Inadequate tissue sample size
  • Improper fixation or preservation
  • Missing patient identification or documentation

Understanding Your Results

Results indicate whether breast cancer cells express estrogen and/or progesterone receptors, which influences treatment strategies.
Positive ER/PR: Cancer likely to respond to hormonal therapy such as tamoxifen
Negative ER/PR: Cancer less likely to respond to hormonal therapy, alternative treatments may be considered
Consult an oncologist to interpret results in the context of overall clinical picture
⚠️ When to Consult a Doctor:

Consult a doctor if results are abnormal, for treatment planning, or if there are concerns about breast cancer symptoms.

Limitations

  • Test requires tissue samples from biopsy or surgery
  • Not suitable for screening without clinical indication
  • Results may vary based on tumor heterogeneity

Risks & Considerations

  • Minimal risks associated with biopsy or surgery, such as infection or bleeding
  • No direct risks from the IHC test itself

Interfering Factors

  • Poor tissue fixation quality
  • Improper sample handling
  • Technical errors in staining
  • Use of incorrect antibodies

Compare With Similar Tests

TestIHC ER-PRIHC HER2Ki-67
ComparisonIHC ER-PRTests for HER2 protein expression, often used alongside ER-PR for comprehensive breast cancer profiling.Measures cell proliferation rate, providing additional prognostic information in breast cancer.

Frequently Asked Questions

What is the IHC ER-PR test?
The IHC ER-PR test is an immunohistochemistry test that checks for estrogen and progesterone receptors in breast cancer tissue to guide treatment.
Why is the IHC ER-PR test important?
It helps determine if breast cancer will respond to hormonal therapy, allowing for personalized treatment plans.
How is the IHC ER-PR test performed?
The test is performed on a tissue sample collected via biopsy or surgery, using immunohistochemical staining techniques.
What is the cost of the IHC ER-PR test at DNA Labs India?
The test costs INR 4000, with free home sample collection available across India.
Is home collection available for the IHC ER-PR test?
Yes, DNA Labs India offers free home sample collection for online bookings in numerous cities across India.
How long does it take to get IHC ER-PR test results?
Results are typically available within 3 days after sample collection.
What do positive IHC ER-PR results mean?
Positive results indicate the presence of hormone receptors, suggesting the cancer may respond well to hormonal therapy.
What do negative IHC ER-PR results mean?
Negative results mean hormone receptors are absent, and alternative treatments may be considered.
Is the IHC ER-PR test covered by insurance?
Coverage varies by insurance provider; it is recommended to check with your insurer for details.
Who should take the IHC ER-PR test?
It is recommended for breast cancer patients to determine hormone receptor status for treatment planning.
Are there any risks associated with the IHC ER-PR test?
The test itself has no risks, but the biopsy or surgery for sample collection may have minor risks like infection.
How should I prepare for the IHC ER-PR test?
No special preparation is needed, but ensure you have a doctor's prescription and follow sample collection instructions.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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