Immunoglobulin IgG Synthesis Index & Rate Test
Short Name: IgG Synthesis Index & Rate Test
Also known as: IgG Index Test, IgG Synthesis Rate Test
Immunoglobulin IgG Synthesis Index & Rate Test test available at DNA Labs India for ₹3,500. Uses BCG, Nephelometry, Immunoturbidimetry on CSF and Serum samples. Results in Results are typically available by the next day after sample collection, with reports delivered via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
This test is used to diagnose and monitor Multiple Sclerosis and other autoimmune diseases by measuring IgG synthesis in CSF and serum, helping assess immune activity in the central nervous system.
- Test Code
- 875
- Price
- ₹3,500
- Sample Type
- CSF and Serum
- Result Time
- Results are typically available by the next day after sample collection, with reports delivered via online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- BCG, Nephelometry, Immunoturbidimetry
Sample Collection
CSF and serum samples must be collected at the same date and time. Inform the doctor about any medications, allergies, or existing conditions.
Method: Lumbar puncture for CSF collection, venipuncture for serum collection
Laboratory Analysis
CSF is collected via lumbar puncture by a healthcare professional. Blood is drawn from a vein in the arm for serum. The procedure may cause slight discomfort.
Report Delivery
Samples should be labeled correctly with collection date and time, and shipped refrigerated or frozen to the laboratory as per stability guidelines.
Timeline: Results are typically available by the next day after sample collection, with reports delivered via online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
This test is used to diagnose and monitor Multiple Sclerosis and other autoimmune diseases by measuring IgG synthesis in CSF and serum, helping assess immune activity in the central nervous system.
How to Prepare
- Ensure both CSF and serum are collected simultaneously.
- Use sterile containers for CSF and SST for serum.
- Ship samples within the stability timeframe to avoid degradation.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"The IgG Synthesis Index & Rate Test is essential for evaluating intrathecal IgG production, aiding in the diagnosis of conditions like Multiple Sclerosis."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Samples not collected at the same time
- Hemolyzed or contaminated samples
- Insufficient sample volume
- Improper labeling or storage
Understanding Your Results
If you have symptoms like persistent fatigue, neurological issues, or if test results are abnormal, consult a neurologist for further evaluation and management.
Limitations
- ⚠Not specific to Multiple Sclerosis; elevated IgG can occur in other conditions
- ⚠Requires CSF collection, which is invasive
- ⚠Results should be interpreted in conjunction with clinical findings and other tests
Risks & Considerations
- ●Headache after lumbar puncture
- ●Risk of infection at collection site
- ●Rarely, bleeding or nerve damage
- ●Discomfort during blood draw
Interfering Factors
- ●Contamination of CSF sample
- ●Hemolysis in serum sample
- ●Improper sample storage
- ●Concurrent infections or inflammation
Compare With Similar Tests
| Test | Immunoglobulin IgG Synthesis Index & Rate Test | ANA Test | RF Test | ESR Test | MRI Brain |
|---|---|---|---|---|---|
| Comparison | Immunoglobulin IgG Synthesis Index & Rate Test |
Frequently Asked Questions
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