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Immunohistochemistry AFP (Alpha Feto Protein) Test

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Immunohistochemistry AFP (Alpha Feto Protein) Test

Short Name: AFP IHC Test

Also known as: AFP IHC, Alpha Feto Protein Immunohistochemistry

Immunohistochemistry AFP (Alpha Feto Protein) Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor Tissue samples. Results in 5-7 days. Free home collection in 300+ cities across India.

ImmunohistochemistryAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose and monitor cancers such as hepatocellular carcinoma and yolk sac tumors by detecting AFP expression in tissue samples.

Test Code
952
Price
₹3,000
Sample Type
Tumor Tissue
Result Time
5-7 days
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Ensure a copy of the histopathology report, site of biopsy, and clinical history is available.

Method: Biopsy

Step 2

Laboratory Analysis

Tissue sample collected via biopsy procedure.

Step 3

Report Delivery

Sample stored and transported as per guidelines to laboratory.

Timeline: 5-7 days

About This Test

Who Should Get This Test

To diagnose and monitor cancers such as hepatocellular carcinoma and yolk sac tumors by detecting AFP expression in tissue samples.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the histopathology report, site of biopsy, and clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"AFP is an oncofetal antigen useful in identifying yolk sac tumors and hepatocellular carcinoma. Interpret results in clinical context and consult an oncologist for diagnosis."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor Tissue
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy

Sample Stability

Room Temperature
Sample Rejection Criteria:
  • Inadequate tissue sample
  • Missing or incomplete documentation

Understanding Your Results

Results indicate the presence and level of AFP expression in tissue samples, aiding in cancer diagnosis.
📊

No significant AFP expression, unlikely for AFP-related cancers

Level: Negative

📊

Elevated AFP expression suggestive of cancers like hepatocellular carcinoma or yolk sac tumors

Level: Positive

⚠️ When to Consult a Doctor:

If experiencing symptoms like abdominal pain, unexplained weight loss, jaundice, or if AFP levels are elevated, consult an oncologist for further evaluation.

Limitations

  • Not all cancers cause elevated AFP
  • False positives may occur in non-cancerous conditions

Risks & Considerations

  • Minimal risks from biopsy procedure
  • Possible infection or bleeding at biopsy site

Interfering Factors

  • Tissue fixation issues
  • Sample degradation or contamination

Compare With Similar Tests

TestImmunohistochemistry AFP (Alpha Feto Protein) TestSerum AFP TestBiopsy HistopathologyCT Scan Abdomen
ComparisonImmunohistochemistry AFP (Alpha Feto Protein) Test

Frequently Asked Questions

What is the Immunohistochemistry AFP test?
It is a diagnostic test that measures AFP levels in tissue samples to help diagnose and monitor cancers like liver and testicular cancer.
Why is this test performed?
To detect AFP expression in tumors, aiding in cancer diagnosis, staging, and treatment monitoring.
What is the cost of the test in India?
The cost is INR 3000, with free home sample collection available in many cities across India.
How is the sample collected?
A tissue sample is obtained via biopsy and submitted in formalin or as a paraffin-embedded block.
What symptoms might indicate elevated AFP?
Symptoms include abdominal swelling or pain, unexplained weight loss, nausea, fatigue, jaundice, and bloating.
How long does it take to get results?
Results are typically available within 5-7 days, depending on the sample type.
Is home collection available for this test?
Yes, free home sample collection is offered for online bookings in cities like Mumbai, Delhi, Bangalore, and more.
What cancers can this test detect?
It can help detect hepatocellular carcinoma, yolk sac tumors, and sometimes testicular or ovarian cancers.
Is fasting required before the test?
No, fasting is not required, but ensure all necessary documents like histopathology report are provided.
How accurate is the Immunohistochemistry AFP test?
It is a valuable tool but should be used alongside other tests for accurate diagnosis; false positives/negatives can occur.
What should I do if my AFP levels are high?
Consult an oncologist for further evaluation, which may include additional tests like imaging or biopsy.
Can insurance cover this test?
Insurance coverage may vary; check with your provider as it is often not covered, but schemes like PMJAY need verification.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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