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Immunohistochemistry Arginase-1 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Arginase-1 Test

Short Name: IHC Arginase-1 Test

Also known as: Arginase-1 Immunohistochemistry, IHC for Arginase-1

Immunohistochemistry Arginase-1 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue samples. Results in Reports available in 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

ImmunohistochemistryAdult🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect arginase-1 protein in tissues for diagnosing hepatocellular carcinoma and other liver diseases.

Test Code
965
Price
₹3,500
Sample Type
Tumor tissue
Result Time
Reports available in 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Ensure a copy of histopathology report, biopsy site, and clinical history is available.

Method: Biopsy

Step 2

Laboratory Analysis

Sample collected via biopsy procedure performed by a healthcare provider.

Step 3

Report Delivery

Ship sample at room temperature in specified container to the laboratory.

Timeline: Reports available in 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:Provide necessary documents including histopathology report and clinical history.
2
During the Test:Biopsy procedure performed by a healthcare provider to obtain tissue sample.
3
After the Test:Sample is sent to the laboratory for immunohistochemical analysis.

About This Test

Who Should Get This Test

To detect arginase-1 protein in tissues for diagnosing hepatocellular carcinoma and other liver diseases.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
  • Ship at room temperature
  • Provide a copy of the Histopathology report
  • Specify site of biopsy
  • Include clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Arginase-1 is a sensitive and specific marker for Hepatocellular carcinoma. Use this test to confirm hepatocellular origin in metastatic cases and differentiate from other liver tumors."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy

Sample Stability

Room temperature: Stable for 24-48 hours
Refrigerated: Not recommended
Frozen: Not applicable
Sample Rejection Criteria:
  • Inadequate sample volume
  • Missing clinical information
  • Improper fixation of tissue

Understanding Your Results

Interpretation of results should be done by a qualified pathologist. Positive staining indicates presence of arginase-1, suggestive of hepatocellular origin.
Positive: Indicates hepatocellular carcinoma or hepatocellular origin
Negative: Suggests non-hepatocellular tumor
Weakly positive: Requires further evaluation and correlation with clinical findings
⚠️ When to Consult a Doctor:

If you have symptoms like jaundice, abdominal pain, or unexplained weight loss, consult an oncologist or hepatologist for evaluation and possible testing.

Limitations

  • May be positive in some cholangiocarcinoma cases
  • Not definitive for all liver cancers
  • Requires tissue biopsy for analysis

Risks & Considerations

  • Minor risks associated with biopsy procedure
  • Potential for infection or bleeding at biopsy site
  • Discomfort during tissue collection

Interfering Factors

  • Poor tissue fixation
  • Inadequate sample quality
  • Technical errors in staining procedure

Compare With Similar Tests

TestImmunohistochemistry Arginase-1 TestImmunohistochemistry HepPar-1
ComparisonImmunohistochemistry Arginase-1 TestSimilar marker for hepatocellular carcinoma, but Arginase-1 is often more sensitive and specific.

Frequently Asked Questions

What is the Immunohistochemistry Arginase-1 Test?
It is a diagnostic test that detects arginase-1 protein in tissue samples, primarily used to diagnose hepatocellular carcinoma and confirm hepatocellular origin in tumors.
How much does the Immunohistochemistry Arginase-1 Test cost?
At DNA Labs India, the test costs Rs 3500.0, which includes sample collection and processing.
What sample is required for this test?
A tumor tissue biopsy fixed in 10% Formal-saline or as a Formalin fixed paraffin embedded block is required.
Is home collection available for this test?
Yes, DNA Labs India offers free home collection for online bookings across many cities in India.
How long does it take to get results?
Results are typically available within 5-7 days after sample receipt at the laboratory.
What symptoms might indicate the need for this test?
Symptoms such as fatigue, abdominal pain, jaundice, weight loss, or unexplained pain may warrant evaluation by a healthcare provider for possible testing.
How is the test performed?
The tissue sample is processed and stained using immunohistochemistry techniques to detect arginase-1 protein, then examined under a microscope.
Is the biopsy procedure painful?
The biopsy may cause some discomfort, but local anesthesia is typically used to minimize pain during sample collection.
Can this test diagnose all types of liver cancer?
It is highly sensitive and specific for hepatocellular carcinoma, but may be positive in some cases of cholangiocarcinoma; it is not definitive for all liver cancers.
What should I do before the test?
Ensure you have a copy of your histopathology report, specify the biopsy site, and provide your clinical history to the healthcare provider.
Is the test covered by insurance?
Coverage varies by insurance plan; it is advisable to check with your provider. The test is not covered under government schemes like PMJAY or CGHS without verification.
Where is this test available?
DNA Labs India offers this test in numerous cities across India, including Mumbai, Delhi, Bangalore, and many more, with home collection services.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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