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Immunohistochemistry Ber-Ep4 (EpCAM) Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Ber-Ep4 (EpCAM) Test

Short Name: Ber-Ep4 IHC Test

Also known as: Ber-Ep4 Test, EPCAM Test

Immunohistochemistry Ber-Ep4 (EpCAM) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports are typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

ImmunohistochemistryAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the Immunohistochemistry Ber-Ep4 (EpCAM) test is to detect the expression of the EPCAM protein in tissue samples, aiding in the diagnosis and differentiation of various epithelial-derived cancers, including pulmonary adenocarcinoma, mesothelioma, basal cell carcinoma, and squamous cell carcinoma.

Test Code
910
Price
₹3,500
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Reports are typically available within 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the Histopathology report, site of biopsy, and clinical history.

Method: Biopsy or Surgery

Step 2

Laboratory Analysis

Sample is obtained via biopsy or surgical excision under sterile conditions.

Step 3

Report Delivery

Tissue is fixed in 10% Formal-saline or embedded in paraffin block and shipped at room temperature.

Timeline: Reports are typically available within 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:Ensure all pre-test documentation is provided and the tissue sample is properly collected and fixed.
2
During the Test:The test is performed in the laboratory using immunohistochemistry techniques with the Ber-Ep4 antibody.
3
After the Test:Results are reviewed by a pathologist and reported within the specified turnaround time.

About This Test

Who Should Get This Test

The purpose of the Immunohistochemistry Ber-Ep4 (EpCAM) test is to detect the expression of the EPCAM protein in tissue samples, aiding in the diagnosis and differentiation of various epithelial-derived cancers, including pulmonary adenocarcinoma, mesothelioma, basal cell carcinoma, and squamous cell carcinoma.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
  • Ship at room temperature
  • Include a copy of the Histopathology report, site of biopsy, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"The Ber-Ep4 test is essential for differentiating epithelial-derived cancers, guiding precise diagnosis and treatment planning in oncology."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy or Surgery

Sample Stability

Stable at room temperature for transport when properly fixed
Sample Rejection Criteria:
  • Insufficient tissue sample
  • Improper fixation or container
  • Missing required documentation

Understanding Your Results

Results are interpreted based on the presence or absence of EPCAM expression in the tissue sample, as evaluated by a pathologist.
📊

Positive

EPCAM is expressed, indicating epithelial origin and potentially associated with malignancies such as adenocarcinoma or basal cell carcinoma.

📊

Negative

EPCAM is not expressed, suggesting non-epithelial origin or absence of EPCAM overexpression, which may help differentiate from mesothelioma or squamous cell carcinoma.

⚠️ When to Consult a Doctor:

Consult a doctor if you have symptoms of cancer such as unexplained weight loss, fatigue, persistent cough, or abnormal tissue findings, to determine if this test is appropriate.

Limitations

  • May not detect all types of epithelial cancers
  • Possible false positives or negatives due to technical factors
  • Requires interpretation by an experienced pathologist
  • Not a standalone diagnostic tool; should be used with clinical correlation

Risks & Considerations

  • Minimal risks as the test is performed on already obtained tissue samples
  • Risks from biopsy or surgery are separate and should be discussed with the treating physician

Interfering Factors

  • Improper tissue fixation or processing
  • Degraded sample quality
  • Antibody cross-reactivity or batch variations

Frequently Asked Questions

What is the Immunohistochemistry Ber-Ep4 (EpCAM) test?
It is a diagnostic test that uses antibodies to detect the epithelial cell adhesion molecule (EPCAM) in tissue samples, aiding in cancer diagnosis.
When is the Ber-Ep4 test recommended?
It is recommended when cancer is suspected, for differential diagnosis of epithelial tumors, or when biopsy results show abnormalities.
How is the Ber-Ep4 test performed?
The test is performed on tissue samples from biopsies or surgeries, processed with the Ber-Ep4 antibody to identify EPCAM presence.
What does a positive result mean?
A positive result indicates EPCAM expression, suggesting an epithelial origin and potential association with cancers like adenocarcinoma.
What does a negative result mean?
A negative result means EPCAM is not expressed, which may help differentiate from mesothelioma or squamous cell carcinoma.
What is the cost of the Ber-Ep4 test in India?
The cost is INR 3500, with discounts available for online bookings and home collection services.
Is home sample collection available for this test?
Yes, free home collection is offered for online bookings across numerous cities in India.
How long does it take to get results?
Results are typically available within 5-7 days after sample receipt, with daily sample processing by 6 pm.
What sample is required for the Ber-Ep4 test?
A tumor tissue sample fixed in 10% Formal-saline or as a Formalin fixed paraffin embedded block is required.
Is fasting required for this test?
No, fasting is not required. Pre-test information includes providing histopathology report and clinical history.
What cancers can the Ber-Ep4 test help detect?
It can help detect epithelial-derived cancers such as breast, ovarian, lung, and colorectal cancers, and differentiate between pulmonary adenocarcinoma and mesothelioma.
How accurate is the Ber-Ep4 test?
The test is highly specific when performed correctly, but accuracy depends on sample quality and expert interpretation by a pathologist.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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