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DNA Labs India

Immunohistochemistry BRAF V600E Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry BRAF V600E Test

Also known as: BRAF V600E Mutation Test, BRAF Mutation Detection, IHC BRAF V600E

Immunohistochemistry BRAF V600E Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. samples. Results in Reports available: Sample daily by 6 pm; Report block: 5 days, Tissue biopsy: 5 days, Tissue large complex: 7 days.. Free home collection in 300+ cities across India.

ImmunohistochemistryNot specified🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

The purpose of the Immunohistochemistry BRAF V600E Test is to detect the BRAF V600E mutation in tumor tissues, which is critical for diagnosing certain cancers and guiding targeted therapy decisions.

Test Code
904
Price
₹3,500
Sample Type
Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
Result Time
Reports available: Sample daily by 6 pm; Report block: 5 days, Tissue biopsy: 5 days, Tissue large complex: 7 days.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the Histopathology report, site of biopsy, and clinical history.

Method: Tissue Biopsy

Step 2

Laboratory Analysis

Standard tissue biopsy procedure performed by a healthcare professional.

Step 3

Report Delivery

Sample is preserved and shipped to the laboratory for analysis.

Timeline: Reports available: Sample daily by 6 pm; Report block: 5 days, Tissue biopsy: 5 days, Tissue large complex: 7 days.

Patient Instructions

1
Before the Test:Ensure all required documents, including histopathology report and clinical history, are available.
2
During the Test:The test involves immunohistochemical staining of tissue sections in a laboratory setting.
3
After the Test:Results are reviewed by a pathologist and reported to the referring physician.

About This Test

Who Should Get This Test

The purpose of the Immunohistochemistry BRAF V600E Test is to detect the BRAF V600E mutation in tumor tissues, which is critical for diagnosing certain cancers and guiding targeted therapy decisions.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the Histopathology report, site of biopsy, and clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for identifying BRAF V600E mutations to guide targeted therapy in cancer patients, improving treatment outcomes and survival rates."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSubmit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
ContainerFormal-saline or FFPE block
Collection MethodTissue Biopsy

Sample Stability

Formalin-fixed tissue: stable at room temperature
FFPE blocks: stable for years if stored properly
Sample Rejection Criteria:
  • Inadequate sample volume
  • Improper fixation
  • Missing clinical information

Understanding Your Results

Interpretation of the Immunohistochemistry BRAF V600E Test results involves assessing the presence or absence of the BRAF V600E mutation in the submitted tissue sample.
📊

Positive

Indicates presence of BRAF V600E mutation, suggesting potential responsiveness to BRAF inhibitor therapies. Consult an oncologist for treatment options.

📊

Negative

Indicates absence of BRAF V600E mutation. Other mutations or pathways may be involved; clinical correlation and further testing may be needed.

⚠️ When to Consult a Doctor:

Consult your oncologist immediately after receiving test results to discuss diagnosis, treatment options, and next steps.

Limitations

  • ⚠Test may not detect all BRAF mutations, only V600E
  • ⚠Results depend on sample adequacy
  • ⚠Not suitable for liquid biopsy

Risks & Considerations

  • ●Minor discomfort during biopsy
  • ●Infection or bleeding at biopsy site (rare)
  • ●No direct risks from the test itself

Interfering Factors

  • ●Poor tissue fixation
  • ●Inadequate sample quality
  • ●Technical errors in staining

Frequently Asked Questions

What is the BRAF V600E mutation?
The BRAF V600E mutation is a genetic alteration in the BRAF gene that leads to uncontrolled cell growth, commonly found in cancers like melanoma and colorectal cancer.
Why is the Immunohistochemistry BRAF V600E Test performed?
It is performed to detect the BRAF V600E mutation in tumor tissues to guide targeted therapy decisions and improve treatment outcomes.
What are the symptoms of BRAF V600E mutation?
Symptoms vary by cancer type but may include skin lesions, unexplained weight loss, changes in bowel habits, difficulty swallowing, or lumps in the neck.
How is the test sample collected?
The sample is collected via tissue biopsy, submitted as formalin-fixed or FFPE block, and shipped to the lab with a histopathology report.
What is the cost of the Immunohistochemistry BRAF V600E Test?
The cost at DNA Labs India is INR 3500, with free home collection available in many cities.
How long does it take to get results?
Results are typically available within 5 to 7 days, depending on sample complexity.
Is home collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What cancers are associated with BRAF V600E?
It is associated with melanoma, colorectal cancer, thyroid cancer, hairy cell leukemia, and others.
How accurate is the test?
The test is highly accurate for detecting the V600E mutation using validated immunohistochemical methods.
What should I do if the test is positive?
If positive, consult your oncologist to discuss targeted therapy options and treatment plans.
Are there any risks to the test?
Risks are minimal and related to the biopsy procedure, such as infection or bleeding; the test itself is non-invasive after sample collection.
Can this test be used for screening?
No, it is typically used for diagnostic purposes in patients with suspected or confirmed cancer, not for general screening.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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