Immunohistochemistry Cathepsin D Test
Short Name: Cathepsin D IHC Test
Also known as: Cathepsin D Immunohistochemistry, IHC Cathepsin D Test, Cathepsin D Tissue Analysis
Immunohistochemistry Cathepsin D Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue (biopsy or surgical specimen) samples. Results in 5-7 days from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To measure Cathepsin D expression in tissues for diagnosing and managing cancers such as breast, ovarian, and gastric cancer, assessing tumor aggressiveness, and informing treatment strategies.
- Test Code
- 899
- Price
- ₹3,000
- Sample Type
- Tumor tissue (biopsy or surgical specimen)
- Result Time
- 5-7 days from sample receipt
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history. Ensure the tissue sample is obtained via biopsy or surgery.
Method: Biopsy or surgery
Laboratory Analysis
Tumor tissue is collected in a sterile manner, typically by a healthcare professional during biopsy or surgical procedure.
Report Delivery
The tissue sample is immediately placed in appropriate fixative (10% formal-saline or formalin) and transported to the lab at room temperature.
Timeline: 5-7 days from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
To measure Cathepsin D expression in tissues for diagnosing and managing cancers such as breast, ovarian, and gastric cancer, assessing tumor aggressiveness, and informing treatment strategies.
How to Prepare
- Submit tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature
- Include a copy of the histopathology report
- Provide site of biopsy and detailed clinical history
- Ensure sample is labeled correctly with patient details
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Cathepsin D expression is a key prognostic marker in breast cancer; elevated levels often correlate with aggressive tumors and poorer survival, aiding in personalized treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate tissue sample
- Improperly fixed or contaminated specimen
- Missing clinical history or biopsy details
- Sample degradation or autolysis
Understanding Your Results
Consult an oncologist if the test shows high Cathepsin D expression, or if results are abnormal, for further evaluation and management of cancer.
Limitations
- ⚠Not a standalone diagnostic tool; must be interpreted with histopathology and clinical data
- ⚠Sensitivity and specificity may vary based on cancer type
- ⚠Does not provide genetic information
- ⚠Results are semi-quantitative and subject to observer variability
Risks & Considerations
- ●Risks associated with biopsy or surgical procedure (e.g., bleeding, infection)
- ●No direct risks from the test itself, as it is performed on excised tissue
Interfering Factors
- ●Improper tissue fixation or processing
- ●Delay in sample transport
- ●Inadequate tissue sample size
- ●Use of incorrect fixatives
- ●Pre-analytical errors in handling
Compare With Similar Tests
| Test | Immunohistochemistry Cathepsin D Test | Immunohistochemistry ER/PR Test | Immunohistochemistry HER2 Test |
|---|---|---|---|
| Comparison | Immunohistochemistry Cathepsin D Test |
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