Immunohistochemistry CD117 Test
Short Name: CD117 IHC Test
Also known as: c-kit Test, CD117 Staining
Immunohistochemistry CD117 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block samples. Results in Reports typically available in 5-7 days from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To detect the presence of CD117 protein in tissue samples for diagnosis of GISTs and other cancers.
- Test Code
- 916
- Price
- ₹3,000
- Sample Type
- Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Result Time
- Reports typically available in 5-7 days from sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Method: Biopsy
Laboratory Analysis
Sample collected via biopsy procedure by a healthcare professional.
Report Delivery
Store sample appropriately and transport to lab at room temperature.
Timeline: Reports typically available in 5-7 days from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To detect the presence of CD117 protein in tissue samples for diagnosis of GISTs and other cancers.
How to Prepare
- Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
- Ship at room temperature.
- Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"CD117 testing is crucial for accurate diagnosis and treatment planning in GISTs and other CD117-expressing tumors."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Improperly fixed samples
- Insufficient tissue quantity
- Missing clinical history
Understanding Your Results
Positive CD117
Suggestive of GIST or other CD117-expressing tumors. Further confirmatory tests may be needed.
Negative CD117
Less likely for GIST, consider other diagnoses based on clinical context.
Weak or focal expression
May require additional testing or clinical correlation.
If you have symptoms such as abdominal pain, nausea, vomiting, or abnormal test results, consult an oncologist or your healthcare provider immediately.
Limitations
- ⚠This test only detects CD117 expression and does not provide information on other markers. Correlation with histopathology is essential for accurate diagnosis.
Risks & Considerations
- ●Biopsy-related risks such as bleeding or infection
- ●Minimal risk from sample processing in lab
Interfering Factors
- ●Inadequate sample fixation
- ●Tissue degradation
- ●Improper staining techniques
Compare With Similar Tests
| Test | Immunohistochemistry CD117 Test | KIT Mutation Analysis | PDGFRA Immunohistochemistry | BRAF V600E Mutation Test | DOGI-1 Immunohistochemistry |
|---|---|---|---|---|---|
| Comparison | Immunohistochemistry CD117 Test | Detects genetic mutations in KIT gene for targeted therapy planning. | Tests for PDGFRA protein, another marker in GISTs. | Used in melanoma and other cancers, not specific to GISTs. | Another marker for GIST diagnosis, often used with CD117. |
Frequently Asked Questions
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