Immunohistochemistry CD31 Test
Short Name: CD31 IHC Test
Also known as: CD31 Immunohistochemistry, Endothelial Marker CD31, CD31 IHC Staining
Immunohistochemistry CD31 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block samples. Results in 5-7 days from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry CD31 Test is to confirm the presence of CD31 protein in tissue samples, aiding in the diagnosis of vascular tumors, particularly angiosarcoma, and other diseases involving abnormal blood vessel growth. It helps in differentiating between benign and malignant lesions and guides therapeutic decisions.
- Test Code
- 924
- Price
- ₹3,000
- Sample Type
- Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Result Time
- 5-7 days from sample receipt
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the Histopathology report, site of biopsy, and clinical history. Ensure tissue is properly preserved in 10% Formal-saline or as a Formalin fixed paraffin embedded block.
Method: Tissue biopsy collection
Laboratory Analysis
Tissue biopsy is collected by a healthcare professional, typically during a surgical procedure or biopsy, following standard sterile protocols.
Report Delivery
Monitor the biopsy site for signs of infection or bleeding. Follow up with your healthcare provider for results and further guidance.
Timeline: 5-7 days from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry CD31 Test is to confirm the presence of CD31 protein in tissue samples, aiding in the diagnosis of vascular tumors, particularly angiosarcoma, and other diseases involving abnormal blood vessel growth. It helps in differentiating between benign and malignant lesions and guides therapeutic decisions.
How to Prepare
- Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
- Ship the sample at room temperature.
- Include a copy of the Histopathology report, site of biopsy, and clinical history.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"CD31 is a key endothelial marker used in immunohistochemistry to identify vascular tumors like angiosarcoma, aiding in precise diagnosis and treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate or insufficient tissue sample
- Improper fixation or preservation
- Missing clinical history or biopsy details
- Sample contamination or damage
Understanding Your Results
Consult a healthcare professional if you experience symptoms such as unusual lumps, persistent swelling, abnormal bleeding, or after a biopsy report indicating vascular abnormalities. Early diagnosis is key for effective treatment.
Limitations
- ⚠Subjective interpretation by pathologist
- ⚠May not detect all vascular tumors
- ⚠Requires adequate clinical history for accuracy
- ⚠Limited to tissue samples; not applicable for blood tests
Risks & Considerations
- ●As with any biopsy, risks include bleeding, infection, pain at the biopsy site
- ●Minimal risks associated with laboratory processing
- ●False positives or negatives possible, requiring clinical correlation
Interfering Factors
- ●Poor tissue fixation
- ●Inadequate sample size
- ●Technical errors in staining
- ●Contamination or degradation of tissue
Compare With Similar Tests
| Test | Immunohistochemistry CD31 Test | Immunohistochemistry CD34 | Immunohistochemistry Factor VIII | Biopsy for Angiosarcoma |
|---|---|---|---|---|
| Comparison | Immunohistochemistry CD31 Test | CD34 is another endothelial marker, but CD31 is more specific for mature endothelial cells and commonly used for angiosarcoma diagnosis. | Factor VIII is also an endothelial marker; CD31 is often preferred for its higher sensitivity in certain vascular tumors. | This test is part of the biopsy analysis, specifically using immunohistochemistry to confirm endothelial origin. |
Frequently Asked Questions
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