Immunohistochemistry CD35 Test
Short Name: CD35 IHC Test
Also known as: Complement Receptor 1, CR1
Immunohistochemistry CD35 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Report: 5-7 days after sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry CD35 Test is to identify and quantify CD35 protein in tissue samples, helping diagnose conditions such as cancer (especially follicular dendritic-cell sarcoma), autoimmune diseases, and infections. It assists pathologists and oncologists in differentiating cell types, guiding treatment strategies, and monitoring disease progression.
- Test Code
- 921
- Price
- ₹3,000
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Report: 5-7 days after sample receipt
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Ensure a copy of the histopathology report, site of biopsy, and clinical history is available.
Method: Tissue Biopsy
Laboratory Analysis
Tissue biopsy is collected under sterile conditions and placed in appropriate fixative.
Report Delivery
Store sample at room temperature and transport to the laboratory promptly.
Timeline: Report: 5-7 days after sample receipt
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry CD35 Test is to identify and quantify CD35 protein in tissue samples, helping diagnose conditions such as cancer (especially follicular dendritic-cell sarcoma), autoimmune diseases, and infections. It assists pathologists and oncologists in differentiating cell types, guiding treatment strategies, and monitoring disease progression.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature
- Provide a copy of the histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is essential for identifying follicular dendritic cells and granulocytes, aiding in the diagnosis of follicular dendritic-cell sarcoma and other conditions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate or improperly fixed tissue
- Missing clinical history or biopsy site information
- Sample degradation or contamination
Understanding Your Results
Positive CD35 Expression
Suggests presence of follicular dendritic cells or granulocytes; may indicate conditions like follicular dendritic-cell sarcoma or immune dysregulation.
Negative CD35 Expression
No detectable CD35 protein; rules out certain cell types but requires further tests for diagnosis.
Weak Staining
Low CD35 expression; may require additional validation or clinical correlation.
Consult your doctor if you have symptoms such as persistent fever, fatigue, joint pain, rash, or unexplained swelling, especially if cancer or autoimmune disease is suspected.
Limitations
- ⚠Not a standalone diagnostic tool; requires correlation with histopathology and clinical history
- ⚠May yield false positives/negatives due to technical issues
- ⚠Limited to protein expression analysis; does not provide genetic information
Risks & Considerations
- ●Minimal risk associated with tissue biopsy, such as infection or bleeding at the site
- ●Allergic reactions to fixatives are rare
Interfering Factors
- ●Poor tissue fixation or handling
- ●Inadequate sample size
- ●Use of incorrect staining protocols
- ●Contamination or degradation of tissue
Compare With Similar Tests
| Test | Immunohistochemistry CD35 Test | Immunohistochemistry CD20 | Immunohistochemistry CD3 | Immunohistochemistry CD68 |
|---|---|---|---|---|
| Comparison | Immunohistochemistry CD35 Test |
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