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DNA Labs India

Immunohistochemistry CD57 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry CD57 Test

Short Name: CD57 IHC Test

Also known as: CD57 Immunohistochemistry, HNK-1 Test, LEU-7 Test

Immunohistochemistry CD57 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry (IHC) on Tumor Tissue samples. Results in Reports are typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

ImmunohistochemistryAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect CD57 expression in tumor tissues for cancer diagnosis, prognosis, and treatment planning, particularly in neuroendocrine tumors, prostate cancer, and Hodgkin lymphoma.

Test Code
889
Price
₹3,000
Sample Type
Tumor Tissue
Result Time
Reports are typically available within 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry (IHC)
Step 1

Sample Collection

Provide histopathology report, site of biopsy, and clinical history.

Method: Biopsy and Tissue Submission

Step 2

Laboratory Analysis

Biopsy performed by healthcare professional, tissue preserved in appropriate fixative.

Step 3

Report Delivery

Sample submitted to laboratory for processing and staining.

Timeline: Reports are typically available within 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:Ensure biopsy is properly fixed in formalin, and all clinical details including histopathology report are provided to the laboratory.
2
During the Test:Tissue sample is processed, sectioned, and stained with anti-CD57 antibody using immunohistochemistry methods, then examined under microscope.
3
After the Test:Pathologist examines stained slides and prepares report with findings on CD57 expression.

About This Test

Who Should Get This Test

To detect CD57 expression in tumor tissues for cancer diagnosis, prognosis, and treatment planning, particularly in neuroendocrine tumors, prostate cancer, and Hodgkin lymphoma.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded (FFPE) block
  • Ship at room temperature
  • Include copy of histopathology report, site of biopsy, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is essential for assessing CD57 expression in tumors, which can aid in the diagnosis and prognosis of certain cancers, particularly neuroendocrine tumors and Hodgkin lymphoma."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor Tissue
Sample VolumeAdequate tissue sample as per biopsy
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy and Tissue Submission

Sample Stability

Stable at room temperature for short-term transport
FFPE blocks can be stored long-term at room temperature
Sample Rejection Criteria:
  • Inadequate tissue sample
  • Improper fixation or preservation
  • Missing clinical information or histopathology report

Understanding Your Results

CD57 expression is interpreted as positive or negative based on immunohistochemical staining. Positive indicates presence of CD57 marker in tumor cells, which may be associated with certain cancers and immune conditions.
📊

Suggests CD57 expression, commonly seen in neuroendocrine tumors, prostate adenocarcinoma, or lymphocyte-predominant Hodgkin lymphoma. May indicate specific tumor type or immune response.

📊

No CD57 expression detected in the tissue, which may help rule out certain tumor types or indicate absence of this marker.

⚠️ When to Consult a Doctor:

If CD57 expression is positive, consult an oncologist for further evaluation, diagnosis confirmation, and treatment planning. Discuss results with your healthcare provider for personalized care.

Limitations

  • Qualitative test only, not quantitative
  • Requires expert interpretation by pathologist
  • Not standalone for diagnosis; should be used with other tests
  • Results may vary with tissue processing and fixation

Risks & Considerations

  • Minimal risk associated with biopsy procedure, such as infection or bleeding at biopsy site
  • Allergic reactions to staining reagents are rare
  • No direct risks from the test itself, as it involves tissue analysis

Interfering Factors

  • Poor tissue fixation
  • Inadequate sample size
  • Previous treatment effects (e.g., chemotherapy)
  • Technical errors in staining process

Compare With Similar Tests

TestImmunohistochemistry CD57 TestImmunohistochemistry Panel for TumorsFlow CytometryGenetic TestingBlood CD57 Test (NK Cell Count)
ComparisonImmunohistochemistry CD57 TestCD57 is specific for certain tumors; other markers like CD3, CD20, or cytokeratins may be used for broader tumor classification.IHC CD57 is for fixed tissue sections, while flow cytometry detects CD57 on live cells in suspension; both can assess immune markers but in different contexts.For hereditary cancer syndromes, whereas IHC CD57 evaluates protein expression in tumors for diagnostic purposes.Measures CD57+ natural killer cells in blood for immune assessment, while IHC CD57 assesses expression in tumor tissues for cancer diagnosis.

Frequently Asked Questions

What is the Immunohistochemistry CD57 Test?
It is a diagnostic test that uses immunohistochemistry to detect CD57 protein expression in tumor tissues, aiding in cancer diagnosis.
Why is this test performed?
To identify CD57 expression in tumors, which helps in diagnosing and classifying cancers like neuroendocrine tumors, prostate cancer, and Hodgkin lymphoma.
What sample is required for the test?
Tumor tissue submitted in 10% formal-saline or formalin fixed paraffin embedded (FFPE) block, along with histopathology report, biopsy site, and clinical history.
How is the test conducted?
The tissue is processed, sectioned, and stained with anti-CD57 antibody using immunohistochemistry, then examined under a microscope by a pathologist.
What does a positive CD57 result mean?
It indicates the presence of CD57 expression in the tumor, which is commonly associated with certain cancers such as small cell carcinoma or Hodgkin lymphoma.
What does a negative CD57 result mean?
It suggests no CD57 expression detected in the tissue, which may help rule out certain tumor types or indicate absence of this marker.
How long does it take to get results?
Results are typically available within 5-7 days after the sample is received at the laboratory.
What is the cost of the test?
The Immunohistochemistry CD57 test costs INR 3000 at DNA Labs India, with free home sample collection available.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
Are there any risks associated with the test?
Risks are minimal and mainly related to the biopsy procedure, such as infection or bleeding; the IHC test itself has no direct risks.
What should I do before the test?
Ensure that the biopsy tissue is properly fixed in formalin and provide all required clinical information, including histopathology report.
How should I interpret the results?
Consult your oncologist or pathologist for interpretation; positive results may indicate specific cancer types, while negative results may help in differential diagnosis.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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