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DNA Labs India

Immunohistochemistry CDK-4 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry CDK-4 Test

Short Name: CDK-4 IHC Test

Also known as: CDK4 Immunohistochemistry, IHC for CDK-4, Cyclin-Dependent Kinase 4 Test

Immunohistochemistry CDK-4 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue samples. Results in 5-7 business days from sample receipt. Free home collection in 300+ cities across India.

Diagnostic🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the Immunohistochemistry CDK-4 test is to identify CDK-4 protein expression in tumor tissues, assisting in the diagnosis and differentiation of cancers such as liposarcomas. It provides valuable information for oncologists to determine the specific type of cancer and guide appropriate treatment strategies.

Test Code
984
Price
₹3,000
Sample Type
Tumor tissue
Result Time
5-7 business days from sample receipt
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history to the laboratory.

Method: Biopsy collection by healthcare professional

Step 2

Laboratory Analysis

Tissue biopsy is performed by a qualified healthcare professional, and the sample is collected in appropriate fixative.

Step 3

Report Delivery

The sample is processed and analyzed in the lab using immunohistochemistry methods.

Timeline: 5-7 business days from sample receipt

Patient Instructions

1
Before the Test:Clinical evaluation by a healthcare provider to determine the need for biopsy and testing.
2
During the Test:Laboratory processing of the tissue sample using immunohistochemical staining techniques.
3
After the Test:Report generation with interpretation, and consultation with a pathologist or oncologist if needed.

About This Test

Who Should Get This Test

The purpose of the Immunohistochemistry CDK-4 test is to identify CDK-4 protein expression in tumor tissues, assisting in the diagnosis and differentiation of cancers such as liposarcomas. It provides valuable information for oncologists to determine the specific type of cancer and guide appropriate treatment strategies.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
  • Ship samples at room temperature
  • Include a copy of the histopathology report, site of biopsy, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"CDK-4 testing is essential for accurate diagnosis and treatment planning in sarcomas, helping differentiate between liposarcoma subtypes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue
Sample VolumeAs required for biopsy
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy collection by healthcare professional

Sample Stability

Room temperature
Refrigerator
Frozen
Sample Rejection Criteria:
  • Insufficient tissue sample
  • Improperly fixed or degraded sample
  • Missing clinical information or histopathology report

Understanding Your Results

Results indicate the presence or absence of CDK-4 protein expression in the submitted tissue sample.
📊

Positive CDK-4 expression

Suggests overexpression, commonly seen in well-differentiated and dedifferentiated liposarcomas

📊

Negative CDK-4 expression

May indicate absence, seen in benign lipomatous lesions, pleomorphic liposarcoma, myxoid liposarcoma, or other sarcomas

📊

Uncertain or equivocal results

Recommend correlation with clinical history and additional tests, and consultation with a pathologist

⚠️ When to Consult a Doctor:

If you experience symptoms like unexplained weight loss, persistent pain, or skin changes, or if test results are abnormal, consult an oncologist for further evaluation and treatment.

Limitations

  • Test detects only CDK-4 protein, not other markers
  • Requires adequate tumor tissue sample
  • Results should be correlated with histopathology and clinical findings

Risks & Considerations

  • Minimal risk associated with biopsy procedure, such as infection or bleeding
  • No direct risks from the immunohistochemistry test itself

Interfering Factors

  • Improper tissue fixation
  • Sample degradation during transport
  • Technical errors in staining or processing

Compare With Similar Tests

TestImmunohistochemistry CDK-4 TestBiopsyImmunohistochemistry PanelCT Scan or MRIBlood Tests for Tumor Markers
ComparisonImmunohistochemistry CDK-4 Test

Frequently Asked Questions

What is CDK-4?
CDK-4 stands for Cyclin-Dependent Kinase 4, a protein involved in cell cycle regulation. Abnormalities can lead to cancer development.
Why is the Immunohistochemistry CDK-4 test done?
It is performed to detect CDK-4 protein expression in tumors, helping diagnose and differentiate cancers like liposarcomas.
How much does the CDK-4 test cost in India?
The cost at DNA Labs India is INR 3000.0, with free home sample collection available.
What sample is required for this test?
A tumor tissue sample fixed in 10% Formal-saline or as a formalin-fixed paraffin-embedded block is needed.
Is fasting required before the test?
No, fasting is not required as the test involves tissue biopsy, not blood sampling.
How long does it take to get results?
Results are typically available within 5-7 business days from sample receipt.
What do positive CDK-4 results indicate?
Positive results suggest CDK-4 overexpression, commonly associated with well-differentiated and dedifferentiated liposarcomas.
Can this test detect all cancers?
No, it is specific for CDK-4 expression and mainly used for sarcomas; other tests are needed for comprehensive cancer diagnosis.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What should I bring for the test?
You need to provide a copy of the histopathology report, site of biopsy, and clinical history.
Are there any risks with the biopsy?
Biopsy procedures carry minimal risks like infection or bleeding, but the immunohistochemistry test itself is safe.
How can I book the test?
You can book online through DNA Labs India's website or contact them via phone or WhatsApp for assistance.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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