Immunohistochemistry CDK-4 Test
Short Name: CDK-4 IHC Test
Also known as: CDK4 Immunohistochemistry, IHC for CDK-4, Cyclin-Dependent Kinase 4 Test
Immunohistochemistry CDK-4 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue samples. Results in 5-7 business days from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry CDK-4 test is to identify CDK-4 protein expression in tumor tissues, assisting in the diagnosis and differentiation of cancers such as liposarcomas. It provides valuable information for oncologists to determine the specific type of cancer and guide appropriate treatment strategies.
- Test Code
- 984
- Price
- ₹3,000
- Sample Type
- Tumor tissue
- Result Time
- 5-7 business days from sample receipt
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history to the laboratory.
Method: Biopsy collection by healthcare professional
Laboratory Analysis
Tissue biopsy is performed by a qualified healthcare professional, and the sample is collected in appropriate fixative.
Report Delivery
The sample is processed and analyzed in the lab using immunohistochemistry methods.
Timeline: 5-7 business days from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry CDK-4 test is to identify CDK-4 protein expression in tumor tissues, assisting in the diagnosis and differentiation of cancers such as liposarcomas. It provides valuable information for oncologists to determine the specific type of cancer and guide appropriate treatment strategies.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship samples at room temperature
- Include a copy of the histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"CDK-4 testing is essential for accurate diagnosis and treatment planning in sarcomas, helping differentiate between liposarcoma subtypes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient tissue sample
- Improperly fixed or degraded sample
- Missing clinical information or histopathology report
Understanding Your Results
Positive CDK-4 expression
Suggests overexpression, commonly seen in well-differentiated and dedifferentiated liposarcomas
Negative CDK-4 expression
May indicate absence, seen in benign lipomatous lesions, pleomorphic liposarcoma, myxoid liposarcoma, or other sarcomas
Uncertain or equivocal results
Recommend correlation with clinical history and additional tests, and consultation with a pathologist
If you experience symptoms like unexplained weight loss, persistent pain, or skin changes, or if test results are abnormal, consult an oncologist for further evaluation and treatment.
Limitations
- ⚠Test detects only CDK-4 protein, not other markers
- ⚠Requires adequate tumor tissue sample
- ⚠Results should be correlated with histopathology and clinical findings
Risks & Considerations
- ●Minimal risk associated with biopsy procedure, such as infection or bleeding
- ●No direct risks from the immunohistochemistry test itself
Interfering Factors
- ●Improper tissue fixation
- ●Sample degradation during transport
- ●Technical errors in staining or processing
Compare With Similar Tests
| Test | Immunohistochemistry CDK-4 Test | Biopsy | Immunohistochemistry Panel | CT Scan or MRI | Blood Tests for Tumor Markers |
|---|---|---|---|---|---|
| Comparison | Immunohistochemistry CDK-4 Test |
Frequently Asked Questions
What is CDK-4?
Why is the Immunohistochemistry CDK-4 test done?
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What sample is required for this test?
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What do positive CDK-4 results indicate?
Can this test detect all cancers?
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