Immunohistochemistry CDX-2 Test
Short Name: CDX-2 IHC Test
Also known as: CDX-2 Immunohistochemistry Test, IHC CDX-2 Test
Immunohistochemistry CDX-2 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue samples. Results in Reports typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry CDX-2 test is to identify CDX-2 protein expression in cells, which aids in diagnosing colorectal cancer and determining the primary site of metastatic carcinomas. It helps clinicians differentiate intestinal cancers from other types, ensuring accurate diagnosis and tailored treatment plans.
- Test Code
- 928
- Price
- ₹3,500
- Sample Type
- Tumor tissue
- Result Time
- Reports typically available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the Histopathology report, site of biopsy, and clinical history. Ensure sample is collected and fixed properly.
Method: Biopsy or surgical specimen collection
Laboratory Analysis
Tissue biopsy or surgical specimen is collected under sterile conditions and placed in appropriate fixative.
Report Delivery
Sample is processed in the lab for immunohistochemical staining; no special post-collection care needed for the patient.
Timeline: Reports typically available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry CDX-2 test is to identify CDX-2 protein expression in cells, which aids in diagnosing colorectal cancer and determining the primary site of metastatic carcinomas. It helps clinicians differentiate intestinal cancers from other types, ensuring accurate diagnosis and tailored treatment plans.
How to Prepare
- Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Ship at room temperature
- Provide a copy of the Histopathology report, Site of biopsy, and Clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for identifying the primary site in metastatic carcinomas of unknown origin, aiding in targeted treatment planning for colorectal cancer."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate tissue sample
- Improper fixation or container
- Missing clinical history or histopathology report
Understanding Your Results
Positive CDX-2 Staining
Suggests carcinoma of intestinal origin, commonly associated with colorectal cancer.
Negative CDX-2 Staining
Indicates tumor likely not of intestinal origin; further investigation needed for primary site.
Consult an oncologist if you experience symptoms like rectal bleeding, abdominal pain, or unexplained weight loss, or if test results are abnormal or inconclusive.
Limitations
- ⚠Not a standalone diagnostic test; requires correlation with clinical and other pathological findings
- ⚠May yield false negatives in some tumor types
- ⚠Limited to detecting intestinal differentiation only
Risks & Considerations
- ●Minimal risks from biopsy procedure, such as infection or bleeding
- ●No direct risks from the immunohistochemistry test itself
Interfering Factors
- ●Poor tissue fixation
- ●Inadequate sample size
- ●Use of improper fixatives
- ●Technical errors in staining process
Compare With Similar Tests
| Test | Immunohistochemistry CDX-2 Test | Colonoscopy | Biopsy with H&E Staining |
|---|---|---|---|
| Comparison | Immunohistochemistry CDX-2 Test | Direct visualization of colon; CDX-2 IHC is molecular confirmation. | Histological assessment; CDX-2 IHC adds specific protein detection. |
Frequently Asked Questions
What is the Immunohistochemistry CDX-2 Test?
What is the cost of the CDX-2 IHC Test in India?
Why is the CDX-2 Test recommended?
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What are the symptoms of colorectal cancer?
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