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DNA Labs India

Immunohistochemistry CK-5/6 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry CK-5/6 Test

Short Name: IHC CK-5/6 Test

Also known as: Cytokeratin 5/6 Immunohistochemistry, CK-5/6 Stain

Immunohistochemistry CK-5/6 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports available in 5 to 7 days depending on sample type.. Free home collection in 300+ cities across India.

Diagnostic🏠 Home Collection

🩺 Medically Reviewed By

Overview

To identify CK-5/6 expression in tumors for diagnosis and differentiation of cancer types, such as squamous, urothelial, and myoepithelial carcinomas, and to distinguish mesotheliomas from adenocarcinomas.

Test Code
931
Price
₹3,000
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Reports available in 5 to 7 days depending on sample type.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history.

Method: Biopsy

Step 2

Laboratory Analysis

Tissue biopsy performed by healthcare professional.

Step 3

Report Delivery

Ship sample at room temperature.

Timeline: Reports available in 5 to 7 days depending on sample type.

Patient Instructions

1
Before the Test:Consult with an oncologist or pathologist for test recommendation.
2
During the Test:Biopsy sample is analyzed in the laboratory using immunohistochemistry methods.
3
After the Test:Results are reviewed and interpreted by a pathologist.

About This Test

Who Should Get This Test

To identify CK-5/6 expression in tumors for diagnosis and differentiation of cancer types, such as squamous, urothelial, and myoepithelial carcinomas, and to distinguish mesotheliomas from adenocarcinomas.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The IHC CK-5/6 test is essential for accurate subtyping of cancers, particularly in differentiating mesotheliomas from adenocarcinomas, guiding targeted treatment plans."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy

Sample Stability

Store at room temperature for up to 48 hours
Avoid freezing
Sample Rejection Criteria:
  • Improperly fixed sample
  • Insufficient tissue
  • Missing clinical information

Understanding Your Results

Results indicate presence or absence of CK-5/6 expression, which helps in cancer subtyping.
Positive staining suggests presence of CK-5/6, common in squamous, urothelial, and myoepithelial carcinomas.
Negative staining may indicate adenocarcinoma, useful in differentiating from mesothelioma.
Results should be interpreted by a pathologist in context of clinical findings.
⚠️ When to Consult a Doctor:

If experiencing symptoms like unexplained weight loss, fatigue, or persistent pain, or for ongoing cancer diagnosis and management.

Limitations

  • Not definitive alone; requires correlation with histopathology and clinical data
  • May have false negatives or positives based on sample quality

Risks & Considerations

  • Biopsy-related risks such as infection or bleeding, but minimal

Interfering Factors

  • Poor sample fixation
  • Insufficient tissue
  • Technical errors in staining

Compare With Similar Tests

TestImmunohistochemistry CK-5/6 TestImmunohistochemistry CK-7 TestImmunohistochemistry p63 TestBiopsy Analysis
ComparisonImmunohistochemistry CK-5/6 Test

Frequently Asked Questions

What is the Immunohistochemistry CK-5/6 test?
It is a test that uses antibodies to detect CK-5/6 proteins in tissue samples, aiding in cancer diagnosis.
When is this test recommended?
When cancer is suspected, particularly for squamous cell, urothelial, or myoepithelial carcinomas, or to differentiate mesothelioma.
How is the sample collected?
A biopsy sample is taken from the suspected area and preserved in formalin or formal-saline.
What is the cost of the test?
The test costs INR 3000 at DNA Labs India, with home collection available.
Is the test covered by insurance?
It may not be covered; check with your insurance provider for details.
How long does it take to get results?
Results are typically available within 5 to 7 days after sample collection.
What does a positive result mean?
Positive indicates CK-5/6 expression, helping identify specific cancer types for treatment planning.
Are there any risks associated with the test?
The test itself is safe, but biopsy collection carries minor risks like infection or bleeding.
How should I prepare for the test?
Provide necessary medical history and reports; no special preparation is needed.
Can this test be done at home?
Home sample collection is available in many cities across India for convenience.
What other tests are related to CK-5/6?
Related tests include IHC CK-7, CK-20, p63, and TTF-1 for comprehensive cancer diagnosis.
Who interprets the test results?
A pathologist interprets the results in consultation with the referring oncologist.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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