Immunohistochemistry Cyclin-D1 Test
Short Name: IHC Cyclin-D1 Test
Also known as: IHC Cyclin D1, Cyclin D1 Immunohistochemistry
Immunohistochemistry Cyclin-D1 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports available in 5-7 days via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry Cyclin-D1 Test is to identify cyclin D1 protein overexpression in tissue samples, which is crucial for diagnosing and classifying cancers such as mantle cell lymphoma, breast cancer, and head and neck cancers. It aids in confirming malignancy, guiding treatment decisions, and monitoring disease progression.
- Test Code
- 930
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Reports available in 5-7 days via online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the Histopathology report, Site of biopsy, and Clinical history.
Method: Tissue biopsy collection
Laboratory Analysis
Tissue biopsy is collected via surgical or core needle procedure under local anesthesia.
Report Delivery
Specimen is preserved in 10% formal-saline or embedded in paraffin for analysis.
Timeline: Reports available in 5-7 days via online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry Cyclin-D1 Test is to identify cyclin D1 protein overexpression in tissue samples, which is crucial for diagnosing and classifying cancers such as mantle cell lymphoma, breast cancer, and head and neck cancers. It aids in confirming malignancy, guiding treatment decisions, and monitoring disease progression.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature
- Include a copy of the Histopathology report, Site of biopsy, and Clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for identifying cyclin D1 overexpression in cancers like mantle cell lymphoma, aiding in precise diagnosis and treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate sample volume
- Improper fixation
- Missing clinical details
Understanding Your Results
Positive for cyclin D1 overexpression
Suggests malignancy, such as mantle cell lymphoma or other cyclin D1-driven cancers
Negative for cyclin D1 overexpression
May indicate absence of cyclin D1-related malignancy, but clinical correlation is essential
Consult an oncologist if the test results are positive or if symptoms persist despite negative results.
Limitations
- ⚠Results are semi-quantitative and may require correlation with other tests
- ⚠False negatives possible if cyclin D1 is not overexpressed
- ⚠Tissue heterogeneity can affect results
Risks & Considerations
- ●Minimal risks from biopsy collection, such as infection or bleeding
- ●Rare allergic reactions to staining agents
Interfering Factors
- ●Improper tissue fixation
- ●Inadequate sample quality
- ●Antibody cross-reactivity
Frequently Asked Questions
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