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Immunohistochemistry Cytokeratin-20 (CK-20) Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Cytokeratin-20 (CK-20) Test

Short Name: CK-20 Test

Also known as: CK-20 Immunohistochemistry, Cytokeratin-20 Test

Immunohistochemistry Cytokeratin-20 (CK-20) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue samples. Results in Report available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

ImmunohistochemistryAdult🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect CK-20 antigen in tissue samples for diagnosing cancers such as colorectal, bladder, and urothelial carcinoma, and to aid in determining primary site in carcinomas of unknown origin.

Test Code
933
Price
₹3,500
Sample Type
Tumor tissue
Result Time
Report available within 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the Histopathology report, Site of biopsy, and Clinical history.

Method: Biopsy or surgery

Step 2

Laboratory Analysis

Tissue sample collected via biopsy or surgical procedure.

Step 3

Report Delivery

Sample sent to laboratory in specified container at room temperature.

Timeline: Report available within 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:Ensure a tissue sample is available from biopsy or surgery, along with histopathology report and clinical history.
2
During the Test:Tissue sample is processed and analyzed using immunohistochemistry to detect CK-20.
3
After the Test:Results are compiled into a report and delivered via chosen method. Follow-up with physician recommended.

About This Test

Who Should Get This Test

To detect CK-20 antigen in tissue samples for diagnosing cancers such as colorectal, bladder, and urothelial carcinoma, and to aid in determining primary site in carcinomas of unknown origin.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the Histopathology report, Site of biopsy, and Clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"CK-20 is crucial for identifying primary sites in carcinomas of unknown origin, aiding in targeted treatment plans and improving diagnostic accuracy."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue
Sample VolumeAs required
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy or surgery
Sample Rejection Criteria:
  • Inadequate tissue sample
  • Improper fixation or labeling

Understanding Your Results

Results indicate the presence or absence of CK-20 antigen in the tissue sample, aiding in cancer diagnosis.
📊

Positive

CK-20 antigen detected, suggestive of cancer cells; consult oncologist for further evaluation.

📊

Negative

No CK-20 antigen detected; does not rule out cancer; correlate with clinical findings.

⚠️ When to Consult a Doctor:

If you experience symptoms like blood in urine/stool, abdominal pain, or unexplained weight loss, or if test results are positive, consult an oncologist promptly.

Limitations

  • Should be used in conjunction with other tests like CK-7 for accurate diagnosis
  • Not definitive alone for cancer staging

Risks & Considerations

  • Minimal risks from biopsy, such as infection or bleeding
  • Rare allergic reactions to fixatives

Interfering Factors

  • Poor tissue quality
  • Improper fixation

Frequently Asked Questions

What is the Immunohistochemistry Cytokeratin-20 (CK-20) Test?
It is a diagnostic test that detects CK-20 antigen in tissue samples to help diagnose cancers like colorectal and bladder cancer.
Why is the CK-20 test recommended?
It is recommended to identify cancer cells, determine primary site in carcinomas of unknown origin, and guide treatment decisions.
How is the CK-20 test performed?
A tissue sample from biopsy or surgery is analyzed in the lab using immunohistochemistry to detect CK-20 expression.
What symptoms might indicate a need for this test?
Symptoms include blood in urine/stool, abdominal pain, difficulty urinating, changes in bowel habits, and unexplained weight loss.
What is the cost of the CK-20 test in India?
The cost at DNA Labs India is INR 3500, which includes analysis and report.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection across many cities in India.
How long does it take to get CK-20 test results?
Results are typically available within 5-7 days after sample receipt.
What does a positive CK-20 result mean?
A positive result indicates the presence of CK-20 antigen, suggesting cancer cells; further consultation with an oncologist is advised.
What should I do if my CK-20 test is positive?
Consult an oncologist immediately for further evaluation and treatment planning.
Are there any risks associated with the biopsy for this test?
Risks are minimal and may include infection or bleeding at the biopsy site, but are rare.
Can the CK-20 test be used for all types of cancer?
It is specific for certain cancers like colorectal and bladder cancer, and useful in carcinomas of unknown origin.
How accurate is the CK-20 test?
The test is highly accurate for detecting CK-20 expression, but should be interpreted in context with other clinical findings and tests.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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