Immunohistochemistry Desmin Test
Short Name: IHC Desmin Test
Also known as: Desmin IHC Test, Desmin Staining
Immunohistochemistry Desmin Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Results typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry Desmin Test is to detect the presence of Desmin protein in tissue samples, aiding in the diagnosis of muscle disorders and tumors. It helps differentiate muscle-derived tumors from other types, guide treatment decisions, and monitor disease progression.
- Test Code
- 988
- Price
- ₹3,000
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Results typically available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Ensure all relevant medical documents, including histopathology report, biopsy site details, and clinical history, are available for submission.
Method: Tissue biopsy collection
Laboratory Analysis
Sample collection performed by qualified medical personnel through biopsy procedure.
Report Delivery
Tissue sample is preserved and sent to the laboratory for processing and analysis.
Timeline: Results typically available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry Desmin Test is to detect the presence of Desmin protein in tissue samples, aiding in the diagnosis of muscle disorders and tumors. It helps differentiate muscle-derived tumors from other types, guide treatment decisions, and monitor disease progression.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature
- Provide a copy of the histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The Desmin test is crucial for diagnosing muscle-derived tumors and disorders. Early detection through IHC analysis can guide treatment decisions and improve patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate sample size or quality
- Missing clinical history or biopsy details
- Improper fixation or preservation
- Sample contamination
Understanding Your Results
Positive
Presence of Desmin protein suggests muscle cell origin, consistent with muscle disorders or tumors like Rhabdomyosarcoma or Leiomyosarcoma. Correlation with clinical findings is essential.
Negative
Absence of Desmin protein may indicate a non-muscle origin or other conditions. Further diagnostic tests may be recommended based on clinical context.
Consult a doctor if experiencing symptoms of muscle disorders such as unexplained weakness, pain, or movement difficulties, or upon recommendation by a healthcare provider for suspected muscle tumors.
Limitations
- ⚠Cannot distinguish between benign and malignant tumors alone
- ⚠Requires correlation with clinical and histopathological findings
- ⚠Limited to detecting Desmin protein; other markers may be needed for comprehensive diagnosis
Risks & Considerations
- ●Minimal risks associated with the test itself; biopsy procedure may carry risks such as infection or bleeding at the site
Interfering Factors
- ●Improper tissue fixation
- ●Delayed sample processing
- ●Technical errors in staining procedure
- ●Contamination of sample
Compare With Similar Tests
| Test | Immunohistochemistry Desmin Test | Creatine Kinase Test | Electromyography (EMG) | Muscle Biopsy | MRI Scan |
|---|---|---|---|---|---|
| Comparison | Immunohistochemistry Desmin Test | Blood test for muscle enzymes; less specific for tumor diagnosis. | Measures electrical activity in muscles; functional assessment, not protein-based. | Direct tissue examination; IHC Desmin adds specificity for protein detection. | Imaging for structural damage; does not provide molecular information. |
Frequently Asked Questions
What is the Immunohistochemistry Desmin Test?
Why is the Desmin Test performed?
How is the sample collected for this test?
What does a positive Desmin result indicate?
What are the symptoms that may require this test?
How long does it take to get the results?
Is the Desmin Test covered by insurance?
Can this test be done at home?
What is the cost of the Immunohistochemistry Desmin Test?
Are there any risks associated with the test?
How should I prepare for the test?
What other tests are related to muscle disorder diagnosis?
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