Immunohistochemistry Glial Fibrillary Acidic Protein (GFAP) Test
Short Name: GFAP IHC Test
Also known as: GFAP immunohistochemistry, Glial Fibrillary Acidic Protein stain
Immunohistochemistry Glial Fibrillary Acidic Protein (GFAP) Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue samples. Results in Report available in 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To diagnose and characterize glial tumors and other neurological conditions by detecting GFAP expression in tissue samples, aiding in clinical decision-making.
- Test Code
- 935
- Price
- ₹3,000
- Sample Type
- Tumor tissue
- Result Time
- Report available in 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history. Ensure tissue is properly fixed in 10% formal-saline or formalin.
Method: Biopsy
Laboratory Analysis
Biopsy procedure performed by a healthcare professional. Tissue is collected and immediately placed in appropriate fixative.
Report Delivery
Submit tissue to the laboratory. Avoid contamination and ensure proper labeling.
Timeline: Report available in 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To diagnose and characterize glial tumors and other neurological conditions by detecting GFAP expression in tissue samples, aiding in clinical decision-making.
How to Prepare
- Use 10% formal-saline or formalin for fixation
- Ship at room temperature
- Include clinical history and biopsy site details
- Ensure tissue block is labeled correctly
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This immunohistochemistry test is essential for identifying glial tumors, aiding in accurate diagnosis and personalized treatment planning for neurological conditions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Improperly fixed tissue
- Inadequate sample volume
- Missing clinical information
- Contaminated or damaged sample
Understanding Your Results
Positive GFAP staining
Suggests glial tumor origin, such as astrocytoma or glioblastoma. Correlate with histopathology and clinical findings.
Negative GFAP staining
Unlikely glial tumor; consider other diagnoses. Additional markers may be required.
Weak or focal staining
May indicate low-grade tumors or mixed histology; further evaluation recommended.
If you experience persistent neurological symptoms like headaches, seizures, or memory loss, or if your test results are abnormal, consult an oncologist or neurologist for further evaluation.
Limitations
- ⚠Results are qualitative and may require correlation with clinical findings
- ⚠Not definitive for tumor grading; additional tests may be needed
- ⚠Limited to tissue analysis; does not detect blood-based biomarkers
- ⚠Interpretation depends on pathologist expertise
Risks & Considerations
- ●Minor risks associated with biopsy procedure (e.g., bleeding, infection)
- ●False positives/negatives possible, requiring clinical correlation
Interfering Factors
- ●Improper tissue fixation or processing
- ●Delay in sample preservation
- ●Inadequate sample size
- ●Technical errors in staining procedure
Compare With Similar Tests
| Test | Immunohistochemistry Glial Fibrillary Acidic Protein (GFAP) Test | ||||
|---|---|---|---|---|---|
| Comparison | Immunohistochemistry Glial Fibrillary Acidic Protein (GFAP) Test | Imaging modality that detects structural abnormalities; GFAP IHC provides cellular-level confirmation. | Quick imaging for gross lesions; GFAP IHC is tissue-based for precise tumor typing. | Often used together with GFAP for comprehensive tumor profiling. | Identifies mutations; GFAP IHC focuses on protein expression for immediate diagnosis. |
Frequently Asked Questions
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