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DNA Labs India

Immunohistochemistry Glypican-3 (GPC3) Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Glypican-3 (GPC3) Test

Also known as: GPC3 Test, Glypican-3 IHC Test

Immunohistochemistry Glypican-3 (GPC3) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Report: 5-7 days depending on sample type. Free home collection in 300+ cities across India.

Immunohistochemistry🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect glypican-3 expression in tissue samples for the diagnosis of hepatocellular carcinoma and other GPC3-expressing tumors.

Test Code
999
Price
₹3,500
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Report: 5-7 days depending on sample type
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the Histopathology report, Site of biopsy, and Clinical history.

Method: Tissue Biopsy

Step 2

Laboratory Analysis

Your sample is analyzed using Immunohistochemistry in our laboratory.

Step 3

Report Delivery

A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.

Timeline: Report: 5-7 days depending on sample type

About This Test

Who Should Get This Test

To detect glypican-3 expression in tissue samples for the diagnosis of hepatocellular carcinoma and other GPC3-expressing tumors.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
  • Ship at room temperature
  • Include a copy of the histopathology report, site of biopsy, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The GPC3 test is a valuable tool in the differential diagnosis of liver tumors and other malignancies expressing glypican-3, aiding in accurate treatment planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodTissue Biopsy

Sample Stability

Room Temperature
Refrigerator
Frozen

Understanding Your Results

Results indicate the presence or absence of glypican-3 staining in the tissue sample.
📊

Positive

Presence of GPC3 staining, suggesting malignancy such as hepatocellular carcinoma or other GPC3-expressing tumors. Correlation with clinical and histological findings is essential.

📊

Negative

Absence of GPC3 staining, indicating no significant expression. However, negative results do not entirely rule out cancer; consider other diagnostic tests and clinical context.

⚠️ When to Consult a Doctor:

Consult an oncologist or specialist if you experience symptoms of liver cancer, have a positive test result, or are at high risk for liver cancer due to underlying conditions.

Frequently Asked Questions

What is the Immunohistochemistry Glypican-3 (GPC3) Test?
The GPC3 Test is a diagnostic test that uses immunohistochemistry to detect the presence of glypican-3 protein in tissue samples, aiding in the diagnosis of liver cancer and other tumors.
Why is the GPC3 Test performed?
It is performed to diagnose hepatocellular carcinoma (HCC) and other cancers expressing glypican-3, especially when symptoms or risk factors for liver cancer are present.
What are the symptoms that may indicate a need for the GPC3 Test?
Symptoms include abdominal pain, unexplained weight loss, loss of appetite, abdominal swelling, jaundice (yellowing of skin and eyes), and fatigue.
How much does the GPC3 Test cost in India?
The cost is approximately INR 3500, with discounts available for online bookings and home sample collection.
How is the GPC3 Test performed?
The test is performed on a tissue sample obtained via biopsy. The sample is prepared and stained using immunohistochemistry to detect GPC3 expression under a microscope.
Who should undergo the GPC3 Test?
Individuals diagnosed with or suspected of having liver cancer, those at high risk due to conditions like chronic hepatitis or cirrhosis, and patients with symptoms of liver malignancy.
What sample is required for the GPC3 Test?
A tumor tissue sample in 10% Formal-saline or Formalin fixed paraffin embedded block, along with a copy of the histopathology report, site of biopsy, and clinical history.
How long does it take to get the GPC3 Test results?
Results are typically available within 5-7 days after sample receipt, depending on the sample type and processing.
Is home sample collection available for the GPC3 Test?
Yes, free home sample collection is available for online bookings across numerous cities in India.
What does a positive GPC3 Test result mean?
A positive result indicates the presence of glypican-3 staining, suggesting malignancy such as hepatocellular carcinoma. Clinical correlation is necessary for accurate diagnosis.
Are there any risks associated with the GPC3 Test?
The test itself is non-invasive on the sample; risks are related to the biopsy procedure, such as bleeding or infection, which should be discussed with your doctor.
How accurate is the GPC3 Test?
The GPC3 test is a reliable immunohistochemical marker for certain cancers, but accuracy depends on proper sample handling and interpretation by qualified pathologists.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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