Immunohistochemistry Isocitrate Dehydrogenase (IDH-1) Test
Short Name: IDH-1 Mutation Test
Also known as: IDH-1 Mutation Test, IDH-1 IHC Test, Isocitrate Dehydrogenase Test
Immunohistochemistry Isocitrate Dehydrogenase (IDH-1) Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor Tissue samples. Results in Results available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To identify IDH-1 mutations in tumor tissues for the diagnosis and classification of gliomas and other related cancers.
- Test Code
- 1005
- Price
- ₹3,500
- Sample Type
- Tumor Tissue
- Result Time
- Results available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history.
Method: Biopsy or Surgical Resection
Laboratory Analysis
Tissue sample collected via biopsy or surgical procedure and fixed in appropriate medium.
Report Delivery
Sample processed, stained, and examined by a pathologist for IDH-1 mutation presence.
Timeline: Results available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To identify IDH-1 mutations in tumor tissues for the diagnosis and classification of gliomas and other related cancers.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
- Ship at room temperature.
- Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"IDH-1 mutation testing is crucial for accurate glioma classification per WHO 2016 guidelines, aiding in prognosis and targeted therapy decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
- Inadequate sample volume
- Improper fixation or preservation
- Missing clinical history
Understanding Your Results
Positive
IDH-1 mutation detected, consistent with certain glioma subtypes such as diffuse astrocytomas or oligodendrogliomas.
Negative
No IDH-1 mutation detected, which may indicate other tumor types or glioblastomas without IDH-1 mutation.
If symptoms persist or worsen after a negative result, or for further treatment planning based on positive results, consult an oncologist.
Limitations
- ⚠Test may not detect all IDH-1 mutations
- ⚠Requires sufficient tumor tissue for analysis
Risks & Considerations
- ●Minor risks associated with biopsy procedure, such as infection or bleeding
Interfering Factors
- ●Poor tissue fixation
- ●Inadequate sample size
Frequently Asked Questions
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