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Immunohistochemistry Lambda Light Chains Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Lambda Light Chains Test

Short Name: IHC Lambda Light Chains Test

Also known as: IHC Lambda Light Chains, Lambda Light Chain Immunohistochemistry

Immunohistochemistry Lambda Light Chains Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block samples. Results in Results are typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

Diagnostic🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect and quantify lambda light chains in tissue samples for diagnosing B-cell and plasma cell neoplasms, aiding in the identification of conditions like multiple myeloma and amyloidosis.

Test Code
942
Price
₹3,500
Sample Type
Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
Result Time
Results are typically available within 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history.

Method: Biopsy sample collection

Step 2

Laboratory Analysis

Standard biopsy procedure performed by a qualified professional.

Step 3

Report Delivery

Store sample appropriately at room temperature and send to the laboratory promptly.

Timeline: Results are typically available within 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:No specific preparation required, but ensure all necessary documents like histopathology report and clinical history are provided.
2
During the Test:Sample collection via biopsy; the process is minimally invasive and performed under local anesthesia if needed.
3
After the Test:Await results as per turnaround time; follow up with physician for interpretation and next steps.

About This Test

Who Should Get This Test

To detect and quantify lambda light chains in tissue samples for diagnosing B-cell and plasma cell neoplasms, aiding in the identification of conditions like multiple myeloma and amyloidosis.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is crucial for diagnosing plasma cell disorders and guiding treatment decisions, especially in cases of suspected multiple myeloma."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
Sample VolumeAs required for analysis
ContainerFormalin container or paraffin block
Collection MethodBiopsy sample collection

Sample Stability

Room temperature: Stable for transport
Refrigerated: Not required
Frozen: Not applicable
Sample Rejection Criteria:
  • Insufficient sample size
  • Improper fixation or container
  • Missing clinical information

Understanding Your Results

Results are interpreted based on the presence, intensity, and pattern of lambda light chain staining in tissue samples.
📊

Suggests clonal B-cell or plasma cell proliferation, indicative of neoplastic conditions like multiple myeloma

📊

May indicate non-clonal processes or absence of lambda light chain expression, requiring further clinical evaluation

⚠️ When to Consult a Doctor:

If experiencing symptoms such as bone pain, fatigue, weight loss, or if test results are abnormal, consult an oncologist or hematologist promptly.

Limitations

  • Cannot distinguish between reactive and neoplastic proliferation without clinical correlation
  • Results may vary based on tissue quality and processing

Risks & Considerations

  • Minimal risks from biopsy procedure, such as infection or bleeding
  • Possible discomfort at the biopsy site

Interfering Factors

  • Inadequate tissue fixation
  • Sample degradation or improper storage
  • Technical errors in staining process

Compare With Similar Tests

TestImmunohistochemistry Lambda Light Chains Test
ComparisonImmunohistochemistry Lambda Light Chains Test

Frequently Asked Questions

What is the Immunohistochemistry Lambda Light Chains Test?
It is a diagnostic test that uses antibodies to detect lambda light chains in tissue samples, helping diagnose B-cell and plasma cell neoplasms like multiple myeloma.
Why is this test performed?
This test is performed to identify clonal proliferation of B-cells or plasma cells, aiding in the diagnosis of cancers such as multiple myeloma and amyloidosis.
What are the symptoms of multiple myeloma?
Common symptoms include bone pain, weakness, fatigue, increased susceptibility to infections, weight loss, nausea, and constipation.
How is the test conducted?
The test involves applying specific antibodies to tissue sections from a biopsy sample and examining them under a microscope for lambda light chain expression.
What sample is required for the test?
A tumor tissue sample fixed in 10% formal-saline or as a formalin-fixed paraffin-embedded block is required, along with clinical history and histopathology report.
How long does it take to get the results?
Results are typically available within 5-7 days after the sample is received at the laboratory.
Is home collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What is the cost of the test?
The cost of the Immunohistochemistry Lambda Light Chains Test at DNA Labs India is INR 3500.
What are the risks associated with the test?
Risks are minimal and related to the biopsy procedure, such as potential infection or bleeding at the collection site.
How should I prepare for the test?
No special preparation is needed, but ensure you provide all required documents like the histopathology report and clinical history.
What do the results indicate?
Positive results suggest clonal B-cell or plasma cell proliferation, while negative results may indicate non-clonal conditions; interpretation should be done by a doctor.
Can this test be used for other conditions besides multiple myeloma?
Yes, it can also be used for diagnosing amyloidosis, B-cell lymphomas, and other plasma cell disorders.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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