Immunohistochemistry Langerin Test
Short Name: IHC Langerin Test
Also known as: Langerin IHC, Langerin Immunohistochemistry, IHC for Langerin
Immunohistochemistry Langerin Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block samples. Results in Reports available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The primary purpose of the Immunohistochemistry Langerin Test is to identify the presence of Langerin protein in tissue samples, which is essential for diagnosing Langerhans cell-related disorders and cancers. This test helps confirm diagnoses, guide treatment decisions, and monitor disease progression in conditions such as Langerhans cell histiocytosis, lymphoma, and leukemia.
- Test Code
- 1006
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Result Time
- Reports available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Inform the doctor about any medications, allergies, or bleeding disorders. Follow biopsy or surgery preparation instructions provided by the healthcare facility.
Method: Biopsy or surgical excision
Laboratory Analysis
The sample is collected via biopsy or surgery under local or general anesthesia. The procedure is performed in a clinical setting.
Report Delivery
Apply pressure to the biopsy site to prevent bleeding. Follow wound care instructions. The sample is sent to the lab in specified containers.
Timeline: Reports available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of the Immunohistochemistry Langerin Test is to identify the presence of Langerin protein in tissue samples, which is essential for diagnosing Langerhans cell-related disorders and cancers. This test helps confirm diagnoses, guide treatment decisions, and monitor disease progression in conditions such as Langerhans cell histiocytosis, lymphoma, and leukemia.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature
- Provide a copy of the histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for diagnosing Langerhans cell histiocytosis and related cancers, aiding in precise treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample not in appropriate fixative
- Insufficient tissue quantity
- Missing clinical details or histopathology report
- Contaminated or degraded sample
Understanding Your Results
Positive
Langerin detected, indicating possible Langerhans cell histiocytosis or related condition. Correlation with clinical findings needed.
Negative
Langerin not detected. Consider other diagnoses or repeat testing if clinical suspicion remains.
Consult an oncologist or pathologist if symptoms like unexplained weight loss, skin rashes, or swollen lymph nodes persist, or based on test results for personalized treatment advice.
Limitations
- ⚠Test is specific to Langerin; other markers may be needed for comprehensive diagnosis
- ⚠Results depend on quality of tissue sample
- ⚠Cannot differentiate between benign and malignant conditions alone
- ⚠May require correlation with clinical history and other tests
Risks & Considerations
- ●Infection at biopsy site
- ●Bleeding or hematoma
- ●Allergic reaction to anesthesia
- ●Scarring
Interfering Factors
- ●Improper sample fixation or storage
- ●Use of incorrect antibodies in lab
- ●Contamination or degradation of tissue
- ●Recent use of immunosuppressive medications
Frequently Asked Questions
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