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DNA Labs India

Immunohistochemistry LIN-28 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry LIN-28 Test

Short Name: IHC LIN-28 Test

Also known as: LIN-28 Protein Detection Test, IHC for LIN-28

Immunohistochemistry LIN-28 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Sample by 6 pm daily; reports: 5 days for block, 5 days for biopsy, 7 days for large complex tissues.. Free home collection in 300+ cities across India.

Oncologist🏠 Home Collection

🩺 Medically Reviewed By

Overview

Diagnosis of germ cell tumors and detection of LIN-28 protein expression to aid in cancer diagnosis and treatment planning.

Test Code
900
Price
₹3,500
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Sample by 6 pm daily; reports: 5 days for block, 5 days for biopsy, 7 days for large complex tissues.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history as per pre-test information.

Method: Biopsy

Step 2

Laboratory Analysis

Standard biopsy procedure performed by a healthcare professional to obtain tumor tissue.

Step 3

Report Delivery

Tissue sample is processed and stained for immunohistochemistry analysis.

Timeline: Sample by 6 pm daily; reports: 5 days for block, 5 days for biopsy, 7 days for large complex tissues.

Patient Instructions

1
Before the Test:Ensure all pre-test information, including histopathology report and clinical history, is provided.
2
During the Test:Biopsy tissue is collected and processed for immunohistochemistry staining.
3
After the Test:Monitor for any post-biopsy complications and await results within 5-7 days.

About This Test

Who Should Get This Test

Diagnosis of germ cell tumors and detection of LIN-28 protein expression to aid in cancer diagnosis and treatment planning.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
  • Ship at room temperature
  • Provide a copy of the histopathology report, site of biopsy, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
ContainerFormalin container or paraffin block
Collection MethodBiopsy

Sample Stability

Room temperature: Stable for shipping
Refrigerated or frozen: Not specified
Sample Rejection Criteria:
  • Inadequate sample volume
  • Improperly preserved tissue
  • Missing clinical history

Understanding Your Results

Results of the Immunohistochemistry LIN-28 Test are interpreted based on the presence or absence of LIN-28 protein in the tissue sample.
📊

Positive

LIN-28 protein is detected, which may indicate germ cell tumors or other cancers; further clinical correlation is recommended.

Action: Consult with an oncologist for comprehensive diagnosis and treatment planning.

📊

Negative

LIN-28 protein is not detected; however, symptoms may be due to other conditions.

Action: Discuss results with a physician to explore alternative diagnostic tests.

⚠️ When to Consult a Doctor:

If symptoms such as unexplained weight loss, fatigue, or persistent cough persist, or if test results are positive, consult an oncologist immediately for evaluation.

Limitations

  • Test is specific for LIN-28 and may not detect all cancer types
  • Requires biopsy tissue, not suitable for blood samples

Risks & Considerations

  • Standard biopsy risks such as bleeding, infection, or discomfort at the biopsy site

Interfering Factors

  • Poor tissue preservation
  • Inadequate sample size
  • Technical errors in staining

Frequently Asked Questions

What is the Immunohistochemistry LIN-28 Test?
It is a diagnostic test that uses immunohistochemistry to detect LIN-28 protein in tissue samples, helping diagnose cancers like germ cell tumors.
Why is this test recommended?
It is recommended for patients with symptoms such as unexplained weight loss, fatigue, or persistent cough, which may indicate cancer, to assist in diagnosis.
How is the test performed?
A tissue sample obtained via biopsy is treated with antibodies specific to LIN-28 protein, and presence is detected under a microscope.
What is the cost of the test?
The cost at DNA Labs India is INR 3500, with free home sample collection available across India.
Is home collection available?
Yes, free home collection is available for online bookings in multiple cities across India.
How long does it take to get results?
Results are typically available within 5-7 days, depending on the tissue type.
What do the results mean?
A positive result indicates LIN-28 protein presence, suggesting possible malignancy; a negative result means no detection, but further evaluation may be needed.
Is the test covered by insurance?
Insurance coverage varies; it is not typically covered under government schemes like PMJAY or CGHS, but check with private insurers.
What are the symptoms that indicate the need for this test?
Symptoms include unexplained weight loss, fatigue, persistent fever, night sweats, swollen lymph nodes, difficulty breathing, or persistent cough.
How should I prepare for the test?
No specific preparation like fasting is required, but provide all necessary medical documents as per pre-test information.
Are there any risks associated with the test?
The test involves biopsy, which has minor risks such as bleeding or infection, but these are generally low.
Can this test diagnose all types of cancer?
No, it specifically detects LIN-28 protein associated with germ cell tumors and some other cancers, not all malignancies.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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