Immunohistochemistry MDM2 Test
Short Name: IHC MDM2 Test
Also known as: MDM2 Test, MDM2 Immunohistochemistry Test
Immunohistochemistry MDM2 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports available in 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To detect overexpression of MDM2 protein in tumor tissues for accurate cancer diagnosis, differential diagnosis, and treatment planning, particularly in sarcomas and related cancers.
- Test Code
- 1022
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Reports available in 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history to the laboratory.
Method: Tissue biopsy
Laboratory Analysis
A tissue biopsy is performed by a healthcare professional to collect the tumor sample.
Report Delivery
The tissue sample is processed and stained using immunohistochemistry techniques for MDM2 detection.
Timeline: Reports available in 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To detect overexpression of MDM2 protein in tumor tissues for accurate cancer diagnosis, differential diagnosis, and treatment planning, particularly in sarcomas and related cancers.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
- Ship the sample at room temperature.
- Include a copy of the histopathology report, site of biopsy, and clinical history.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"The Immunohistochemistry MDM2 Test is crucial for diagnosing MDM2-overexpressing cancers such as liposarcoma and osteosarcoma, guiding targeted treatment plans for better outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample not in proper fixative
- Inadequate tissue quantity
- Missing clinical information
Understanding Your Results
Negative
No overexpression of MDM2 protein, may indicate other cancer types or normal tissue.
Positive (weak intensity)
Low-level MDM2 overexpression, may require further testing.
Positive (moderate intensity)
Significant MDM2 overexpression, suggestive of cancers like low-grade osteosarcoma.
Positive (strong intensity)
High MDM2 overexpression, commonly seen in liposarcoma and related tumors.
Consult an oncologist if you experience symptoms such as unexplained weight loss, persistent pain, lumps, or if the test result is positive for MDM2 overexpression.
Limitations
- ⚠Subjective interpretation of staining intensity
- ⚠Not definitive for all cancer types
- ⚠Requires correlation with histopathology and clinical data
Risks & Considerations
- ●Minimal risks from biopsy procedure, such as infection or bleeding
- ●No direct risks from the IHC test itself
Interfering Factors
- ●Poor tissue fixation
- ●Inadequate sample size
- ●Technical errors in staining
- ●Tissue autolysis
Frequently Asked Questions
What is the Immunohistochemistry MDM2 Test?
Why is the MDM2 Test performed?
What is the cost of the MDM2 Test in India?
How is the sample collected for this test?
What does a positive MDM2 result mean?
Are there any risks associated with the MDM2 Test?
How long does it take to get MDM2 Test results?
Is home collection available for the MDM2 Test?
What should I do before the MDM2 Test?
How accurate is the Immunohistochemistry MDM2 Test?
Can the MDM2 Test be used for all types of cancer?
Who should I consult after receiving MDM2 Test results?
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