Immunohistochemistry OLIG2 Test
Short Name: OLIG2 IHC Test
Also known as: OLIG2 Test, IHC OLIG2, Oligodendrocyte Transcription Factor 2 Test
Immunohistochemistry OLIG2 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block samples. Results in 5-7 days from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry OLIG2 test is to identify the expression of OLIG2 protein in tumor tissues, which helps in the accurate diagnosis and classification of brain tumors, especially oligodendroglial tumors. This information is vital for prognosis and selecting appropriate chemotherapy regimens, as these tumors may have different treatment responses.
- Test Code
- 896
- Price
- ₹3,500
- Sample Type
- Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Result Time
- 5-7 days from sample receipt
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history. Ensure proper preservation of the tissue sample in formalin.
Method: Tissue Biopsy
Laboratory Analysis
A tissue sample is obtained via biopsy or surgical resection and immediately placed in 10% formal-saline or formalin for fixation.
Report Delivery
The preserved tissue sample is shipped at room temperature to the laboratory. A copy of the histopathology report and clinical details must accompany the sample.
Timeline: 5-7 days from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry OLIG2 test is to identify the expression of OLIG2 protein in tumor tissues, which helps in the accurate diagnosis and classification of brain tumors, especially oligodendroglial tumors. This information is vital for prognosis and selecting appropriate chemotherapy regimens, as these tumors may have different treatment responses.
How to Prepare
- Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Ship at room temperature
- Provide a copy of the Histopathology report, Site of biopsy and Clinical history
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"The Immunohistochemistry OLIG2 test is essential for differentiating oligodendroglial tumors, which have distinct genetic profiles and treatment responses, aiding in personalized therapy planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient tissue sample
- Improper fixation or preservation
- Missing required documentation like histopathology report
Understanding Your Results
Positive
OLIG2 detected, indicating oligodendroglial lineage, such as oligodendroglioma or oligoastrocytoma.
Negative
OLIG2 not detected, suggesting the tumor may not be of oligodendroglial origin.
If you experience symptoms of brain tumors or have abnormal imaging results, consult an oncologist or neurologist immediately for further evaluation and to discuss the need for this test.
Limitations
- ⚠Not a standalone diagnostic tool; requires correlation with histopathology and other tests
- ⚠May not detect all oligodendroglial tumors if OLIG2 expression is low
- ⚠Results depend on quality of tissue sample and laboratory technique
Risks & Considerations
- ●Infection at biopsy site
- ●Bleeding
- ●Allergic reaction to local anesthesia
- ●Pain or discomfort during biopsy
Interfering Factors
- ●Improper tissue fixation
- ●Antibody cross-reactivity
- ●Inadequate sample size
- ●Contamination during processing
Compare With Similar Tests
| Test | Immunohistochemistry OLIG2 Test | MRI Brain | CT Scan | EGFR Mutation Test | IDH1 Mutation Test |
|---|---|---|---|---|---|
| Comparison | Immunohistochemistry OLIG2 Test |
Frequently Asked Questions
What is the Immunohistochemistry OLIG2 test?
Why is the OLIG2 test performed?
What does a positive OLIG2 result mean?
What sample is required for this test?
Is fasting required before the test?
How much does the Immunohistochemistry OLIG2 test cost?
Is home sample collection available?
How long does it take to get the results?
What are the risks of the biopsy procedure?
Can this test diagnose all brain tumors?
How should I prepare for the test?
Who should I consult for this test?
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