Immunohistochemistry OLIG2 Test
Short Name: OLIG2 Test
Also known as: OLIG2 Immunohistochemistry, Oligodendrocyte Transcription Factor 2 Test, Olig2 Protein Detection
Immunohistochemistry OLIG2 Test test available at DNA Labs India for ₹3,500. Uses Immunohistochemistry on Tumor tissue samples. Results in Reports typically available within 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 3, 2026
Overview
To identify Olig2 protein expression in tumor tissues, aiding in the diagnosis and classification of central nervous system tumors for appropriate therapeutic interventions.
- Test Code
- 1017
- Price
- ₹3,500
- Sample Type
- Tumor tissue
- Result Time
- Reports typically available within 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history. No special preparation needed for the patient, but ensure biopsy is performed by a qualified professional.
Method: Biopsy collection
Laboratory Analysis
Tumor tissue is collected via biopsy procedure, typically under local or general anesthesia, and placed in appropriate fixative.
Report Delivery
Handle tissue sample carefully to avoid damage. Transport to laboratory at room temperature with proper documentation.
Timeline: Reports typically available within 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
To identify Olig2 protein expression in tumor tissues, aiding in the diagnosis and classification of central nervous system tumors for appropriate therapeutic interventions.
How to Prepare
- Use 10% Formal-saline or Formalin fixed paraffin embedded block for sample submission
- Ship samples at room temperature
- Include histopathology report, biopsy site details, and clinical history
- Ensure sample is labeled correctly with patient information
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for identifying specific types of brain tumors, such as glioblastomas and oligodendrogliomas, to guide personalized treatment plans and improve patient outcomes."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Sample not properly fixed
- Inadequate tissue quantity
- Missing documentation or clinical history
- Sample contaminated or hemolyzed
Understanding Your Results
Positive
OLIG2 protein is detected, suggesting a tumor type such as oligodendroglioma or glioblastoma. Correlate with histopathology and clinical findings for definitive diagnosis.
Negative
OLIG2 protein is not detected, which may indicate other tumor types or non-neoplastic conditions. Further diagnostic tests may be recommended.
Consult an oncologist or neurologist if you experience persistent headaches, seizures, vision problems, balance issues, or other neurological symptoms suggestive of a brain or spinal cord tumor.
Limitations
- ⚠Test accuracy depends on sample quality
- ⚠Cannot determine tumor malignancy alone
- ⚠Requires correlation with clinical and histopathological findings
- ⚠Limited to protein expression detection; genetic mutations may need additional tests
Risks & Considerations
- ●Biopsy-related risks: infection, bleeding, or discomfort at biopsy site
- ●Minimal risk from the immunohistochemistry procedure itself
Interfering Factors
- ●Improper sample preservation
- ●Contamination during collection
- ●Inadequate tissue fixation
- ●Use of incorrect staining protocols
Compare With Similar Tests
| Test | Immunohistochemistry OLIG2 Test | Immunohistochemistry GFAP Test | IDH1 Mutation Testing | Ki-67 Proliferation Index |
|---|---|---|---|---|
| Comparison | Immunohistochemistry OLIG2 Test | GFAP is another marker for astrocytic tumors, while OLIG2 is more specific for oligodendroglial tumors. | IDH1 tests for genetic mutations, whereas OLIG2 detects protein expression; both are complementary in brain tumor diagnosis. | Ki-67 measures tumor cell proliferation, while OLIG2 identifies tumor lineage; used together for comprehensive profiling. |
Frequently Asked Questions
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