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Immunohistochemistry p63 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry p63 Test

Short Name: IHC p63 Test

Also known as: p63 Immunohistochemistry, p63 IHC Test, p63 Staining Test

Immunohistochemistry p63 Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block samples. Results in Reports available within 5-7 working days after sample receipt.. Free home collection in 300+ cities across India.

Immunohistochemistry🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To detect p63 protein expression in tissue samples for the diagnosis of squamous cell carcinomas and other tumors with squamous, urothelial, or myoepithelial differentiation.

Test Code
951
Price
₹3,000
Sample Type
Tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
Result Time
Reports available within 5-7 working days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the Histopathology report, site of biopsy, and clinical history.

Method: Biopsy

Step 2

Laboratory Analysis

Tissue sample collected via biopsy procedure.

Step 3

Report Delivery

Sample processed and analyzed in the laboratory.

Timeline: Reports available within 5-7 working days after sample receipt.

Patient Instructions

1
Before the Test:Ensure all required documents are submitted.
2
During the Test:Sample is stained with p63 antibodies and examined microscopically.
3
After the Test:Results are compiled and reported.

About This Test

Who Should Get This Test

To detect p63 protein expression in tissue samples for the diagnosis of squamous cell carcinomas and other tumors with squamous, urothelial, or myoepithelial differentiation.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block.
  • Ship at room temperature.
  • Include a copy of the histopathology report, site of biopsy, and clinical history.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"The p63 immunohistochemistry test is essential for confirming squamous differentiation in tumors, which aids in targeted therapy selection and prognosis assessment."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
ContainerFormalin container
Collection MethodBiopsy

Sample Stability

Stable at room temperature
Refrigeration not required
Freezing not recommended
Sample Rejection Criteria:
  • Insufficient sample
  • Improper fixation
  • Missing clinical documentation

Understanding Your Results

Results are interpreted based on the presence and pattern of p63 staining in tissue sections.
Positive p63 staining suggests squamous differentiation.
Negative staining may indicate non-squamous tumors.
Intensity and percentage of staining are considered for scoring.
⚠️ When to Consult a Doctor:

Consult an oncologist if you have symptoms suggestive of cancer or if biopsy results are abnormal.

Limitations

  • ⚠Not cancer-specific; can be positive in benign conditions
  • ⚠Requires specialized interpretation
  • ⚠Limited to fixed tissue samples

Risks & Considerations

  • ●Minimal risks from biopsy procedure
  • ●Rare allergic reactions to stains

Interfering Factors

  • ●Inadequate tissue fixation
  • ●Suboptimal antigen retrieval
  • ●Sample contamination

Compare With Similar Tests

TestImmunohistochemistry p63 TestImmunohistochemistry CK5/6Biopsy Histopathology
ComparisonImmunohistochemistry p63 TestAnother marker for squamous differentiation, often used with p63.Standard examination of tissue structure, complemented by IHC.

Frequently Asked Questions

What is the Immunohistochemistry p63 Test?
It is a laboratory test that uses antibodies to detect p63 protein in tissue samples, helping diagnose cancers with squamous differentiation.
Why is this test recommended?
Recommended for confirming squamous cell carcinoma, especially in lung, bladder, or breast cancer cases, and for tumor typing.
What does a positive p63 result indicate?
Positive p63 staining suggests the presence of squamous differentiation, common in squamous cell carcinomas.
How is the sample collected for this test?
A tissue biopsy is taken, fixed in formalin, and sent to the lab for processing and staining.
What is the cost of the IHC p63 Test at DNA Labs India?
The cost is INR 3000, inclusive of home sample collection in many Indian cities.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for this test across India.
How long does it take to receive the test results?
Reports are typically available within 5-7 working days after sample collection.
What are the common symptoms of cancer that might require this test?
Symptoms include unexplained weight loss, fatigue, persistent coughing, blood in urine/stool, abnormal lumps, difficulty swallowing, or changes in bowel habits.
Is the biopsy procedure painful?
Biopsy may cause minor discomfort, but local anesthesia is used to minimize pain.
Are there any risks associated with the test?
Risks are minimal and related to biopsy, such as bleeding or infection, but they are rare.
How accurate is the p63 immunohistochemistry test?
The test is highly accurate when performed correctly, but results should be correlated with clinical and histopathological findings.
Can this test be used to diagnose all types of cancer?
No, it is specific for tumors with squamous, urothelial, or myoepithelial differentiation; other cancers may require different markers.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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