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DNA Labs India

Immunohistochemistry PD-L1 SP142 Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry PD-L1 SP142 Test

Short Name: PD-L1 SP142 IHC Test

Also known as: PD-L1 SP142 Ventana Test, PD-L1 SP142 Immunohistochemistry Test

Immunohistochemistry PD-L1 SP142 Test test available at DNA Labs India for ₹11,500. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports available within 5-7 days. Free home collection in 300+ cities across India.

OncologyAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

The PD-L1 SP142 Test serves as a companion diagnostic for Atezolizumab therapy in urothelial carcinoma and triple-negative breast cancer. It helps identify patients whose tumors express PD-L1, making them potential candidates for immunotherapy. The test evaluates the proportion of tumor cells and immune cells expressing PD-L1, which can inform treatment strategies and improve outcomes.

Test Code
1025
Price
₹11,500
Sample Type
Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
Result Time
Reports available within 5-7 days
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

A certified phlebotomist visits your home or you visit our nearest center. The process takes under 5 minutes.

Method: Biopsy

Step 2

Laboratory Analysis

Your sample is analyzed using Immunohistochemistry in our laboratory.

Step 3

Report Delivery

A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.

Timeline: Reports available within 5-7 days

About This Test

Who Should Get This Test

The PD-L1 SP142 Test serves as a companion diagnostic for Atezolizumab therapy in urothelial carcinoma and triple-negative breast cancer. It helps identify patients whose tumors express PD-L1, making them potential candidates for immunotherapy. The test evaluates the proportion of tumor cells and immune cells expressing PD-L1, which can inform treatment strategies and improve outcomes.

How to Prepare

  • Provide a copy of the histopathology report
  • Specify site of biopsy
  • Include clinical history

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is crucial for determining eligibility for immunotherapy in certain cancers."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
ContainerFormalin container
Collection MethodBiopsy

Understanding Your Results

Results indicate the level of PD-L1 expression in the tumor sample. Higher expression may correlate with better response to immunotherapy.
Positive result: PD-L1 expression detected, may indicate eligibility for immunotherapy.
Negative result: No significant PD-L1 expression, alternative treatments may be considered.
Consult with an oncologist for personalized interpretation and next steps.
⚠️ When to Consult a Doctor:

If experiencing symptoms such as unexplained weight loss, fatigue, coughing up blood, difficulty breathing, or swelling, consult a doctor to determine if this test is appropriate.

Risks & Considerations

  • Biopsy procedure may involve minor bleeding or infection
  • Minimal risks associated with tissue sample collection

Frequently Asked Questions

What is the Immunohistochemistry PD-L1 SP142 Test?
This test measures PD-L1 protein levels in tumor tissues to guide immunotherapy decisions for cancers like urothelial carcinoma and triple-negative breast cancer.
Why is the PD-L1 SP142 Test performed?
It is performed to assess if a patient is eligible for immunotherapy, such as Atezolizumab, by determining PD-L1 expression in tumor samples.
How is the test conducted?
The test uses immunohistochemistry on biopsy tissue samples, analyzed by pathologists in the laboratory.
What is the cost of the PD-L1 SP142 Test?
The test costs INR 11500 at DNA Labs India, including free home sample collection.
Is home sample collection available?
Yes, free home collection is available for online bookings across numerous cities in India.
What are the indications for this test?
Indications include urothelial carcinoma, triple-negative breast cancer, non-small cell lung cancer, and other cancers recommended by an oncologist.
How long does it take to get results?
Results are typically available within 5-7 days after sample receipt.
What does a positive result mean?
A positive result indicates PD-L1 expression, which may suggest eligibility for immunotherapy, but interpretation should be done by an oncologist.
What are the risks of the test?
Risks are minimal and relate to the biopsy procedure, such as minor bleeding or infection.
Who should perform this test?
The test should be ordered by an oncologist and performed by expert pathologists in a certified laboratory.
Can the test be used for all cancers?
It is primarily used for specific cancers like urothelial carcinoma, triple-negative breast cancer, and lung cancer, as per companion diagnostic guidelines.
How to prepare for the test?
No special preparation is needed; provide the biopsy sample along with histopathology report and clinical history.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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