Immunohistochemistry PS2 Test
Short Name: IHC pS2 Test
Also known as: IHC pS2 Protein Test, pS2 Immunohistochemistry
Immunohistochemistry PS2 Test test available at DNA Labs India for ₹1,837. Uses Immunohistochemistry on Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block samples. Results in Reports are typically available in 5-7 days, depending on sample type and complexity.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The IHC pS2 test is performed to determine the expression of pS2 protein in breast cancer tissue, which indicates estrogen receptor positivity. This helps in assessing the likelihood of response to hormonal therapy, guiding treatment decisions, and predicting disease progression.
- Test Code
- 1036
- Price
- ₹1,837
- Sample Type
- Tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Result Time
- Reports are typically available in 5-7 days, depending on sample type and complexity.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history to the diagnostic center.
Method: Tissue Biopsy
Laboratory Analysis
A biopsy is performed to remove a small tissue sample from the breast, which is then preserved in formalin or formal-saline.
Report Delivery
The tissue sample is processed in the laboratory for immunohistochemical staining. Patients may experience minor soreness at the biopsy site.
Timeline: Reports are typically available in 5-7 days, depending on sample type and complexity.
Patient Instructions
About This Test
Who Should Get This Test
The IHC pS2 test is performed to determine the expression of pS2 protein in breast cancer tissue, which indicates estrogen receptor positivity. This helps in assessing the likelihood of response to hormonal therapy, guiding treatment decisions, and predicting disease progression.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block
- Ship at room temperature
- Include a copy of the histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The IHC pS2 test is valuable for identifying ER-positive breast cancer, which helps in tailoring hormonal therapy and improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Insufficient tissue sample
- Improper fixation or storage
- Missing clinical information or histopathology report
Understanding Your Results
Consult an oncologist if you experience breast cancer symptoms, have abnormal test results, or need guidance on treatment options based on the IHC pS2 test.
Limitations
- ⚠pS2 expression is not specific to particular histological types of breast cancer
- ⚠In approximately 30% of cases, pS2 may show ER-independent expression, limiting its predictive value
- ⚠Results should be interpreted in conjunction with other clinical and histopathological findings
Risks & Considerations
- ●Minor bleeding or infection at the biopsy site
- ●Discomfort during tissue collection
- ●Rare allergic reactions to staining agents
Interfering Factors
- ●Poor tissue fixation or handling
- ●Inadequate biopsy sample size
- ●Use of incorrect antibodies or staining protocols
Frequently Asked Questions
What is the Immunohistochemistry PS2 Test?
Why is the IHC pS2 Test performed?
What sample is required for the test?
Is fasting required for the IHC pS2 Test?
How is the test conducted?
What are the risks of the test?
How long does it take to get results?
What does a positive result mean?
What does a negative result mean?
What is the cost of the IHC pS2 Test?
Is home sample collection available?
Who should interpret the test results?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.