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Immunohistochemistry TdT Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry TdT Test

Short Name: TdT IHC Test

Also known as: TdT Immunohistochemistry, Terminal Deoxynucleotidyl Transferase Test, IHC TdT

Immunohistochemistry TdT Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue samples. Results in Reports available in 5-7 days after sample receipt.. Free home collection in 300+ cities across India.

Oncologist, Pathologist🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of the Immunohistochemistry TdT Test is to identify the presence of TdT enzyme in cells, which is a marker for immature lymphoid cells. This helps in diagnosing and differentiating various hematological malignancies, such as acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma, guiding treatment decisions.

Test Code
1045
Price
₹3,000
Sample Type
Tumor tissue
Result Time
Reports available in 5-7 days after sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide a copy of the histopathology report, site of biopsy, and clinical history. No fasting required.

Method: Biopsy or surgical specimen collection

Step 2

Laboratory Analysis

Tumor tissue is collected via biopsy or surgical procedure and preserved in 10% formal-saline or as a formalin fixed paraffin embedded block.

Step 3

Report Delivery

Sample is shipped at room temperature to the laboratory. Follow-up with doctor for result interpretation.

Timeline: Reports available in 5-7 days after sample receipt.

Patient Instructions

1
Before the Test:Provide clinical history and histopathology report. No special preparation needed.
2
During the Test:Tissue sample is processed and stained using immunohistochemistry techniques to detect TdT.
3
After the Test:Results are analyzed and reported. Follow up with your doctor for interpretation.

About This Test

Who Should Get This Test

The purpose of the Immunohistochemistry TdT Test is to identify the presence of TdT enzyme in cells, which is a marker for immature lymphoid cells. This helps in diagnosing and differentiating various hematological malignancies, such as acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma, guiding treatment decisions.

How to Prepare

  • Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded (FFPE) block
  • Ship sample at room temperature
  • Include a copy of the histopathology report, site of biopsy, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"Early detection through TdT testing is crucial for managing hematological malignancies. This test helps in accurate diagnosis and treatment planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue
Sample VolumeN/A
Container10% Formal-saline or Formalin fixed paraffin embedded (FFPE) block
Collection MethodBiopsy or surgical specimen collection

Sample Stability

Stable at room temperature for up to 7 days when properly preserved
FFPE blocks can be stored for extended periods at room temperature
Sample Rejection Criteria:
  • Inadequate or degraded sample
  • Missing clinical information or histopathology report
  • Improper sample preservation or container

Understanding Your Results

The Immunohistochemistry TdT Test results are interpreted based on the presence or absence of TdT expression in the submitted tissue. A positive result indicates the presence of immature lymphoid cells, which may be indicative of leukemia or lymphoma. Negative results suggest absence of TdT in mature cells.
📊

Positive for TdT

Presence of TdT enzyme in cells, suggestive of immature lymphoid neoplasms such as acute lymphoblastic leukemia or lymphoblastic lymphoma. Further evaluation is recommended.

📊

Negative for TdT

Absence of TdT enzyme in cells, indicating mature lymphoid cells or other conditions. Clinical correlation is advised.

⚠️ When to Consult a Doctor:

Consult an oncologist or hematologist if test results are abnormal or if symptoms of leukemia or lymphoma persist.

Limitations

  • Not a standalone diagnostic test; results must be correlated with clinical findings and other tests
  • May not detect all subtypes of lymphoid neoplasms
  • Results depend on sample quality and handling

Risks & Considerations

  • Minimal risks associated with sample collection, such as infection or bleeding from biopsy
  • No direct risks from the immunohistochemistry test itself

Interfering Factors

  • Poor tissue preservation or fixation
  • Inadequate sample quantity
  • Technical errors in staining process

Compare With Similar Tests

TestImmunohistochemistry TdT TestBone Marrow BiopsyFlow Cytometry
ComparisonImmunohistochemistry TdT TestBone marrow biopsy examines bone marrow cells, while TdT IHC focuses on specific enzyme expression in tissue samples.Flow cytometry analyzes cell surface markers, whereas TdT IHC detects intracellular enzyme presence in fixed tissues.

Frequently Asked Questions

What is the Immunohistochemistry TdT Test?
It is a diagnostic test that detects the presence of Terminal Deoxynucleotidyl Transferase (TdT) enzyme in cells, used to diagnose leukemia and lymphoma.
Why is the TdT Test performed?
To identify immature lymphoid cells and diagnose hematological malignancies like acute lymphoblastic leukemia and lymphoblastic lymphoma.
How is the sample collected for TdT Test?
Tumor tissue is collected via biopsy or surgery and preserved in formal-saline or as a formalin fixed paraffin embedded block.
What does a positive TdT result mean?
A positive result indicates the presence of TdT enzyme, suggesting immature lymphoid cells and possible leukemia or lymphoma.
What is the cost of the TdT Test in India?
At DNA Labs India, the cost is INR 3000, including home collection in many cities.
Is home collection available for TdT Test?
Yes, free home sample collection is available for online bookings across India.
How long does it take to get TdT Test results?
Results are typically available within 5-7 days after sample collection.
What are the risks of the TdT Test?
Risks are minimal and mainly related to sample collection, such as infection or bleeding from biopsy.
How should I prepare for the TdT Test?
No special preparation is needed. Provide clinical history and histopathology report with the sample.
What is the normal range for TdT expression?
TdT is typically negative in normal mature lymphoid cells; positive expression indicates immature cells.
Can TdT Test diagnose all types of leukemia?
No, it specifically helps diagnose lymphoid leukemias, especially acute lymphoblastic leukemia, and lymphoblastic lymphoma.
Who should interpret the TdT Test results?
Results should be interpreted by an oncologist, hematologist, or pathologist in conjunction with clinical findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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