Immunohistochemistry TdT Test
Short Name: TdT IHC Test
Also known as: TdT Immunohistochemistry, Terminal Deoxynucleotidyl Transferase Test, IHC TdT
Immunohistochemistry TdT Test test available at DNA Labs India for ₹3,000. Uses Immunohistochemistry on Tumor tissue samples. Results in Reports available in 5-7 days after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of the Immunohistochemistry TdT Test is to identify the presence of TdT enzyme in cells, which is a marker for immature lymphoid cells. This helps in diagnosing and differentiating various hematological malignancies, such as acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma, guiding treatment decisions.
- Test Code
- 1045
- Price
- ₹3,000
- Sample Type
- Tumor tissue
- Result Time
- Reports available in 5-7 days after sample receipt.
- Fasting Required
- No
- Method
- Immunohistochemistry
Sample Collection
Provide a copy of the histopathology report, site of biopsy, and clinical history. No fasting required.
Method: Biopsy or surgical specimen collection
Laboratory Analysis
Tumor tissue is collected via biopsy or surgical procedure and preserved in 10% formal-saline or as a formalin fixed paraffin embedded block.
Report Delivery
Sample is shipped at room temperature to the laboratory. Follow-up with doctor for result interpretation.
Timeline: Reports available in 5-7 days after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Immunohistochemistry TdT Test is to identify the presence of TdT enzyme in cells, which is a marker for immature lymphoid cells. This helps in diagnosing and differentiating various hematological malignancies, such as acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma, guiding treatment decisions.
How to Prepare
- Submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded (FFPE) block
- Ship sample at room temperature
- Include a copy of the histopathology report, site of biopsy, and clinical history
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Early detection through TdT testing is crucial for managing hematological malignancies. This test helps in accurate diagnosis and treatment planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Inadequate or degraded sample
- Missing clinical information or histopathology report
- Improper sample preservation or container
Understanding Your Results
Positive for TdT
Presence of TdT enzyme in cells, suggestive of immature lymphoid neoplasms such as acute lymphoblastic leukemia or lymphoblastic lymphoma. Further evaluation is recommended.
Negative for TdT
Absence of TdT enzyme in cells, indicating mature lymphoid cells or other conditions. Clinical correlation is advised.
Consult an oncologist or hematologist if test results are abnormal or if symptoms of leukemia or lymphoma persist.
Limitations
- ⚠Not a standalone diagnostic test; results must be correlated with clinical findings and other tests
- ⚠May not detect all subtypes of lymphoid neoplasms
- ⚠Results depend on sample quality and handling
Risks & Considerations
- ●Minimal risks associated with sample collection, such as infection or bleeding from biopsy
- ●No direct risks from the immunohistochemistry test itself
Interfering Factors
- ●Poor tissue preservation or fixation
- ●Inadequate sample quantity
- ●Technical errors in staining process
Compare With Similar Tests
| Test | Immunohistochemistry TdT Test | Bone Marrow Biopsy | Flow Cytometry |
|---|---|---|---|
| Comparison | Immunohistochemistry TdT Test | Bone marrow biopsy examines bone marrow cells, while TdT IHC focuses on specific enzyme expression in tissue samples. | Flow cytometry analyzes cell surface markers, whereas TdT IHC detects intracellular enzyme presence in fixed tissues. |
Frequently Asked Questions
What is the Immunohistochemistry TdT Test?
Why is the TdT Test performed?
How is the sample collected for TdT Test?
What does a positive TdT result mean?
What is the cost of the TdT Test in India?
Is home collection available for TdT Test?
How long does it take to get TdT Test results?
What are the risks of the TdT Test?
How should I prepare for the TdT Test?
What is the normal range for TdT expression?
Can TdT Test diagnose all types of leukemia?
Who should interpret the TdT Test results?
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