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Immunophenotyping by Flow Cytometry CD16 + 56 Test

DNA Labs India | ISO 9001:2015 Certified

Immunophenotyping by Flow Cytometry CD16 + 56 Test

Also known as: Flow cytometry CD16+56 test, NK cell immunophenotyping, CD16 CD56 flow cytometry

Immunophenotyping by Flow Cytometry CD16 + 56 Test test available at DNA Labs India for ₹5,500. Uses Flow Cytometry on Whole blood or Bone marrow samples. Results in Same-day report if sample received by 9 am.. Free home collection in 300+ cities across India.

Diagnostic🏠 Home Collection

🩺 Medically Reviewed By

Overview

The purpose of this test is to evaluate the presence and function of Natural Killer (NK) cells and other immune cells that express CD16 and CD56 markers. It aids in diagnosing immune deficiencies, monitoring immune responses, and detecting hematological malignancies.

Test Code
1056
Price
₹5,500
Sample Type
Whole blood or Bone marrow
Result Time
Same-day report if sample received by 9 am.
Fasting Required
No
Method
Flow Cytometry
Step 1

Sample Collection

No specific preparation required. Provide brief clinical history.

Method: Venipuncture or bone marrow aspiration

Step 2

Laboratory Analysis

Sample collected via venipuncture or bone marrow aspiration.

Step 3

Report Delivery

Apply pressure to the site. Avoid heavy lifting.

Timeline: Same-day report if sample received by 9 am.

Patient Instructions

1
Before the Test:Provide clinical history. No fasting required.
2
During the Test:Sample collection takes a few minutes via venipuncture or bone marrow aspiration.
3
After the Test:Resume normal activities. Monitor the collection site for any adverse effects.

About This Test

Who Should Get This Test

The purpose of this test is to evaluate the presence and function of Natural Killer (NK) cells and other immune cells that express CD16 and CD56 markers. It aids in diagnosing immune deficiencies, monitoring immune responses, and detecting hematological malignancies.

How to Prepare

  • Collect 3 mL whole blood in EDTA tube and 3 mL in Sodium Heparin tube, or 2 mL bone marrow in Sodium Heparin tube.
  • Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE.
  • Specify time, date, and clinical details on test request form.

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"This test is essential for evaluating NK cell function and aids in diagnosing certain cancers and immune deficiencies."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole blood or Bone marrow
Sample Volume3 mL whole blood or 2 mL bone marrow
ContainerLavender Top (EDTA) tube and Green Top (Sodium Heparin) tube
Collection MethodVenipuncture or bone marrow aspiration

Sample Stability

Room Temperature: 24 hours
Refrigerator: Not applicable
Frozen: Not applicable
Sample Rejection Criteria:
  • Hemolyzed samples
  • Incorrect sample type
  • Improperly labeled samples

Understanding Your Results

Results are interpreted based on the percentage and absolute count of CD16+56 positive cells. Abnormal levels may indicate immune disorders or malignancies.
📊

Elevated CD16+56 cells

📊

Decreased CD16+56 cells

⚠️ When to Consult a Doctor:

If you experience symptoms like persistent fever, frequent infections, or unexplained weight loss, consult your doctor.

Limitations

  • May not detect all immune abnormalities
  • Results should be correlated with clinical findings

Risks & Considerations

  • Minor pain or bruising at the puncture site
  • In rare cases, infection or excessive bleeding

Interfering Factors

  • Hemolyzed samples
  • Recent blood transfusions
  • Certain medications

Frequently Asked Questions

What is Immunophenotyping by Flow Cytometry CD16 + 56 Test?
It is a diagnostic test that uses flow cytometry to analyze immune cells expressing CD16 and CD56 markers, typically Natural Killer (NK) cells, in blood or bone marrow samples.
Why is this test performed?
To evaluate immune function, diagnose immune disorders, monitor treatment for cancers, and identify conditions like leukemia or lymphoma.
What symptoms may require this test?
Symptoms include fever, chills, increased susceptibility to infections, fatigue, weakness, unexplained weight loss, and swollen lymph nodes.
How is the test conducted?
A blood or bone marrow sample is collected and analyzed using flow cytometry technology to identify and quantify CD16+56 positive cells.
Is fasting required for this test?
No, fasting is not required. However, you may need to provide your clinical history.
What is the cost of the test in India?
The cost is INR 5500 at DNA Labs India, which includes home collection and same-day reporting.
How long does it take to get the results?
Results are typically available on the same day if the sample is received by 9 am.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What do the results mean?
Results show the percentage and count of CD16+56 cells. Abnormal levels may indicate immune issues or cancer; consult your doctor for interpretation.
Are there any risks associated with the test?
Risks are minimal and may include slight pain or bruising at the collection site.
Can this test diagnose cancer?
It can help in diagnosing certain cancers, especially hematological malignancies, but is usually part of a comprehensive diagnostic workup.
How should I prepare for the test?
No special preparation is needed. Provide your clinical history and ensure the sample is collected properly.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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