ISG15 Gene Immunodeficiency type 38 NGS Genetic Test
Short Name: ISG15 Immunodeficiency Type 38 Test
Also known as: ISG15 Deficiency, Immunodeficiency Type 38
ISG15 Gene Immunodeficiency type 38 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To diagnose ISG15 gene mutations causing Immunodeficiency Type 38, confirm clinical suspicion, and guide management.
- Test Code
- 5018
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- NGS Technology
Sample Collection
Clinical history of patient and genetic counseling session to draw a pedigree chart of family members affected with ISG15 gene mutations.
Method: Venipuncture
Laboratory Analysis
Standard blood draw procedure using aseptic technique.
Report Delivery
Apply pressure to the puncture site; monitor for any adverse reactions.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose ISG15 gene mutations causing Immunodeficiency Type 38, confirm clinical suspicion, and guide management.
How to Prepare
- Provide clinical history
- Attend genetic counseling session
- Ensure sample is properly labeled
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is essential for diagnosing rare immunodeficiency disorders caused by ISG15 gene mutations, enabling personalized treatment and genetic counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient volume
- Improper labeling
Understanding Your Results
Positive for pathogenic mutation
Confirms diagnosis of ISG15 Immunodeficiency Type 38; genetic counseling and treatment recommended.
Negative for pathogenic mutation
No mutations detected; clinical correlation and further testing may be needed.
Variant of uncertain significance
Further analysis and family studies recommended.
If experiencing recurrent infections, frequent fevers, or other symptoms of immunodeficiency, or if family history suggests genetic disorder.
Limitations
- ⚠May not detect all genetic variants
- ⚠Results require clinical correlation
Risks & Considerations
- ●Minimal risk from blood draw (e.g., bruising, infection)
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
Frequently Asked Questions
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