ITGB1 Gene Leukocyte adhesion deficiency NGS Genetic Test
Short Name: ITGB1 LAD NGS Genetic Test
Also known as: LAD Genetic Test, ITGB1 Mutation Analysis, Leukocyte Adhesion Deficiency Type I Genetic Test
ITGB1 Gene Leukocyte adhesion deficiency NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the ITGB1 gene for the diagnosis of Leukocyte Adhesion Deficiency, enabling early intervention, family screening, and personalized management of immune deficiency disorders.
- Test Code
- 4718
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks from sample receipt
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Ensure genetic counseling session is scheduled to discuss family history and test implications.
Method: Venipuncture or blood drop
Laboratory Analysis
Blood sample collected via venipuncture or blood drop on FTA card by a trained phlebotomist.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Store sample as per instructions for stability.
Timeline: 3 to 4 weeks from sample receipt
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the ITGB1 gene for the diagnosis of Leukocyte Adhesion Deficiency, enabling early intervention, family screening, and personalized management of immune deficiency disorders.
How to Prepare
- Use sterile collection tubes
- Label samples correctly with patient details
- Transport at ambient room temperature
- Avoid hemolysis during blood draw
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for ITGB1 mutations in suspected LAD cases enables timely intervention, reducing infection risks and improving quality of life. Genetic counseling is essential for family planning and management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Incorrect labeling or missing patient information
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of Leukocyte Adhesion Deficiency. Genetic counseling and clinical management recommended.
Variant of uncertain significance
Further testing or family studies may be needed. Consult a geneticist for guidance.
No pathogenic variants detected
LAD due to ITGB1 mutations unlikely, but clinical correlation is advised if symptoms persist.
Consult a doctor if you experience recurrent infections, delayed wound healing, or have a family history of LAD. After testing, discuss results with a geneticist or immunologist for appropriate management.
Limitations
- ⚠May not detect all types of mutations, such as large deletions or intronic variants
- ⚠Requires genetic counseling for accurate interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risks from blood draw, such as bruising or infection
- ●Psychological impact of genetic results; counseling provided
Interfering Factors
- ●Contaminated or degraded DNA sample
- ●Hemolyzed blood sample
- ●Improper sample storage or handling
Compare With Similar Tests
| Test | ITGB1 Gene Leukocyte adhesion deficiency NGS Genetic Test | ITGB2 Gene LAD NGS Genetic Test | Whole Exome Sequencing |
|---|---|---|---|
| Comparison | ITGB1 Gene Leukocyte adhesion deficiency NGS Genetic Test | Targets a different gene associated with LAD Type II; useful if ITGB1 test is negative but symptoms persist. | Broader analysis of all genes; recommended for complex cases or when multiple genes are suspected. |
Frequently Asked Questions
What is the ITGB1 Gene Leukocyte Adhesion Deficiency NGS Genetic Test?
Who should consider getting this test?
What are the common symptoms of Leukocyte Adhesion Deficiency?
How is the test performed?
What is the cost of the ITGB1 Gene LAD NGS Genetic Test?
Is home sample collection available for this test?
How long does it take to get the test results?
What do the test results indicate?
Are there any risks associated with this genetic test?
How accurate is the NGS Genetic Test for LAD?
Can this test be used for prenatal diagnosis?
What should I do if the test result is positive?
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