KCNT1 Gene Epilepsy, nocturnal frontal lobe NGS Genetic Test
Short Name: KCNT1 NGS Test
Also known as: KCNT1-related epilepsy NGS test, Nocturnal Frontal Lobe Epilepsy Genetic Test, KCNT1 gene mutation analysis
KCNT1 Gene Epilepsy, nocturnal frontal lobe NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks from sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this NGS genetic test is to identify disease-causing variants in the KCNT1 gene in individuals with a clinical suspicion of nocturnal frontal lobe epilepsy or related epileptic syndromes. The results help confirm the diagnosis, guide therapeutic decisions, and provide recurrence risk information for family planning.
- Test Code
- 4082
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Results are typically available within 3 to 4 weeks from sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No special preparation is required. A valid physician referral and clinical history are essential. Genetic counseling is recommended before testing to understand the implications.
Method: Venous blood collection / FTA card blood spot
Laboratory Analysis
Blood is collected by a trained phlebotomist using sterile technique. For FTA card, a few drops of blood are placed on the card and allowed to air dry.
Report Delivery
No specific precautions are needed after sample collection.
Timeline: Results are typically available within 3 to 4 weeks from sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this NGS genetic test is to identify disease-causing variants in the KCNT1 gene in individuals with a clinical suspicion of nocturnal frontal lobe epilepsy or related epileptic syndromes. The results help confirm the diagnosis, guide therapeutic decisions, and provide recurrence risk information for family planning.
How to Prepare
- For blood, collect in EDTA vacutainer and mix gently.
- For FTA card, label with patient ID and allow to air dry.
- Do not expose FTA card to moisture or heat.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"For families with KCNT1-related epilepsy, genetic testing is crucial for accurate diagnosis, recurrence risk counseling, and informed family planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood
- Insufficient sample volume
- Mislabeled sample
- Sample received after prolonged transit time (>72 hours unfrozen)
Understanding Your Results
Pathogenic
Likely Pathogenic
VUS
Benign
Consult your neurologist or geneticist if you or your child experience seizures, especially nocturnal seizures, sudden awakening episodes, or unusual motor behaviors during sleep. If this test result is positive, a genetic consultation is recommended to review the implications and management options.
Limitations
- ⚠This test only analyzes the KCNT1 gene, not other epilepsy-related genes.
- ⚠The test may not detect large deletions/duplications or deep intronic variants depending on the NGS protocol.
- ⚠Variants of uncertain significance (VUS) may be reported; further testing may be required.
- ⚠A negative result does not exclude a genetic cause for epilepsy.
- ⚠Predictive testing in asymptomatic individuals requires pre-test genetic counseling.
Risks & Considerations
- ●No significant physical risks
- ●Possible bruising at the injection site
- ●Emotional or psychological impact of genetic results
Interfering Factors
- ●Sample contamination with external DNA
- ●Low DNA quality or quantity
- ●Incomplete coverage of repetitive regions
- ●Maternal cell contamination in prenatal samples
Frequently Asked Questions
What is KCNT1 gene epilepsy?
What are the common symptoms?
How is KCNT1 gene epilepsy diagnosed?
What is the cost of the KCNT1 NGS genetic test in India?
What type of sample is required?
Is fasting required before the test?
How long does it take to get the report?
What does NGS mean?
Will my insurance cover the cost?
Is home collection available?
Why is it important to get raw data, FASTQ, and VCF files?
Can this test be done for prenatal screening?
Related Tests
Angelman Syndrome Test
₹10,000Duchenne / Becker Muscular Dystrophy (DMD / BMD) Gene Mutation Test
₹14,000Episodic Ataxia Type 1 Hotspot Test
₹11,500Episodic Ataxia Comprehensive Profile Hotspot Test
₹16,000Megalencephalic Leukoencephalopathy with Subcortical Cysts Van Der Knaap and Nalband MLC Gene Hotspot Mutation Test
₹7,500Analyzer 18 SMA 18 Test Panel
₹1,755Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.